Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
H00344752-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AADACL2 (NP_997248, 1 a.a. approximately 379 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPDNIEESWK IMALDAIAKT CTFTAMCFEN MRIMRYEEFI SMIFRLDYTQ PLSDEYITVT DTTFVDIPVR LYLPKRKSET RRRAVIYFHG GGFCFGSSKQ RAFDFLNRWT ANTLDAVVVG VDYRLAPQHH FPAQFEDGLA AVKFFLLEKI LTKYGVDPTR ICISGDSSGG NLATAVTQQV QNDAEIKHKI KMQVLLYPGL QITDSYLPSH RENEHGIVLT RDVAIKLVSL YFTKDEALPW AMRRNQHMPL ESRHLFKFVN WSILLPEKYR KDYVYTEPIL GGLSYSLPGL TDSRALPLLA NDSQLQNLPL TYILTCQHDL LRDDGLMYVT RLRNVGVQVV HEHIEDGIHG ALSFMTSPFY LRLGLRIRDM YVSWLDKNL
Target Information
AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear. 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: ADCL2; Arylacetamide deacetylase-like 2; MGC72001
Gene Aliases: AADACL2
UniProt ID: (Human) Q6P093
Entrez Gene ID: (Human) 344752
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support