Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MNYARFITAA SAARNPSPIR TMSEKRADIL SRGPKSMISL AGGLPNPNMF PFKTAVITVE NGKTIQFGEE MMKRALQYSP SAGIPELLSW LKQLQIKLHN PPTIHYQPSQ GQMDLCVTSG SQQGLCKVFE MIINPGDNVL LDEPAYSGTL QSLHPLGCNI INVASDESGI VPDSLRDILS RWKPEDAKNP QKNTPKFLYT VPNGNNPTGN SLTSERKKEI YELARKYDFL IIEDDPYYFL QFNKFRVPTF LSMDVDGRVI RADSFSKIIS SGLRIGFLTG PKPLIERVIL HIQVSTLHPS TFNQLMISQL LHEWGEEGFM AHVDRVIDFY SNQKDAILAA ADKWLTGLAE WHVPAAGMFL WIKVKGINDV KELIEEKAVK MGVLMLPGNA FYVDSSAPSP YLRASFSSAS PEQMDVAFQV LAQLIKESL
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-aminoadipate aminotransferase; 2-aminoadipate transaminase; AadAT; Alpha-aminoadipate aminotransferase; Glycine transaminase AADAT; KAT/AadAT; Kynurenine aminotransferase II; Kynurenine--glyoxylate transaminase AADAT; kynurenine--oxoglutarate; Kynurenine--oxoglutarate aminotransferase II; Kynurenine--oxoglutarate transaminase 2; Kynurenine--oxoglutarate transaminase II; Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial; L kynurenine/alpha aminoadipate aminotransferase; Methionine--glyoxylate transaminase AADAT
Gene Aliases: AADAT; KAT2; KATII; KYAT2
UniProt ID: (Human) Q8N5Z0
Entrez Gene ID: (Human) 51166
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