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Product Details
PA5-20616
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 20 amino acid peptide near the amino terminus of the human Aak1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11154276
Product Specific Information
A suggested positive control is rat spleen tissue lysate.
PA5-20616 can be used with blocking peptide PEP-0736.
Target Information
AAK1 serine/threonine kinase is a member of the NAK family and plays a regulatory role in endocytosis. AAK1 is a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adaptor-associated kinase 1; AP2 associated kinase 1; AP2-associated protein kinase 1; DKFZp686F03202; DKFZp686K16132; FLJ23712; FLJ25931; FLJ31060; FLJ42882; FLJ45252; MGC138170; MGC164568; MGC164570
Gene Aliases: 5530400K14Rik; 9630042K20; AAK1; AU067724; AU067726; BC028270; C79663; D6Ertd245e; KIAA1048; mKIAA1048; R75501; RGD1563580
UniProt ID: (Human) Q2M2I8, (Mouse) Q3UHJ0
Entrez Gene ID: (Human) 22848, (Mouse) 269774, (Rat) 500244
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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