Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MVFPAKRFC LVPSMEGVRW AFSCGTWLPS RAEWLLAVRS IQPEEKERIG QFVFARDAKA AMAGRLMIRK LVAEKLNIPW NHIRLQRTAK GKPVLAKDSS NPYPNFNFNI SHQGDYAVLA AEPELQVGID IMKTSFPGRG SIPEFFHIMK RKFTNKEWET IRSFKDEWTQ LDMFYRNWAL KESFIKAIGV GLGFELQRLE FDLSPLNLDI GQVYKETRLF LDGEEEKEWA FEESKIDEHH FVAVALRKPD GSRHQDVPSQ DDSKPTQRQF TILNFNDLMS SAVPMTPEDP SFWDCFCFTE EIPIRNGTKS (1-309 aa encoded by BC016728)
The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4'-phosphopantetheinyl transferase; AASD-PPT; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; DKFZp566E2346; holo ACP synthase; holo-[acyl-carrier-protein] synthase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; LYS5 ortholog
Gene Aliases: 2010309J24Rik; 2810407B07Rik; AASD-PPT; AASDHPPT; ACPS; CGI-80; HAH-P; HSPC223; LYS2; LYS5; x0005
UniProt ID: (Human) Q9NRN7, (Rat) B2RYJ4, (Mouse) Q9CQF6
Entrez Gene ID: (Human) 60496, (Rat) 300328, (Mouse) 67618
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