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ACAA2 Antibody (PA5-78324) in ICC/IF
ACAA2 Polyclonal Antibody detects ACAA2 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: ACAA2 protein stained by ACAA2 Polyclonal Antibody (Product # PA5-78324) diluted at 1:500. Blue: Hoechst 33342 staining.
Product Details
PA5-78324
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human ACAA2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.01 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 0.1M glycine, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2735422
Product Specific Information
Positive Control: HeLa
Predicted Reactivity: Rat (90%), Zebrafish (80%), Pig (93%), Chicken (83%), Rhesus Monkey (98%), Bovine (92%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ACAA2 (3-Ketoacyl-CoA thiolase) is an enzyme that in humans is encoded by the ACAA2 gene. Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; acetyl-Coenzyme A acyltransferase 2; Acyl-CoA hydrolase, mitochondrial; beta ketothiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; T1
Gene Aliases: 0610011L04Rik; ACAA2; AI255831; AI265397; D18Ertd240e; DSAEC
UniProt ID: (Human) P42765, (Mouse) Q8BWT1
Entrez Gene ID: (Human) 10449, (Mouse) 52538
fatty acid metabolic process
cholesterol biosynthetic process
cellular response to hypoxia
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
negative regulation of mitochondrial membrane permeability involved in apoptotic process
acetyl-CoA metabolic process
lipid metabolic process
fatty acid beta-oxidation
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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