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Product Details
PA5-102963
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ACACB(Accession O00763), corresponding to amino acid residues K34-D84.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2852337
Product Specific Information
Antibody detects endogenous levels of total ACACB.
Target Information
Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage. May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACC-beta; Acetyl-CoA carboxylase 2; acetyl-Coenzyme A carboxylase beta
Gene Aliases: ACACB; ACC2; ACCB; AI597064; AW743042; HACC275
UniProt ID: (Human) O00763, (Mouse) E9Q4Z2
Entrez Gene ID: (Human) 32, (Mouse) 100705
acetyl-CoA metabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
metabolic process
positive regulation of lipid storage
response to organic cyclic compound
negative regulation of fatty acid oxidation
protein homotetramerization
positive regulation of heart growth
malonyl-CoA biosynthetic process
biotin metabolic process
carnitine shuttle
negative regulation of gene expression
regulation of glucose metabolic process
positive regulation of cellular metabolic process
response to nutrient levels
negative regulation of fatty acid beta-oxidation
negative regulation of catalytic activity
energy homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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