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Product Details
16742-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACAD8 Fusion Protein Ag9967 (1-415 aa encoded by BC001964)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLWSGCRRF GARLGCLPGG LRVLVQTGHR SLTSCIDPSM GLNEEQKEFQ KVAFDFAARE MAPNMAEWDQ KELFPVDVMR KAAQLGFGGV YIQTDVGGSG LSRLDTSVIF EALATGCTST TAYISIHNMC AWMIDSFGNE EQRHKFCPPL CTMEKFASYC LTEPGSGSDA ASLLTSAKKQ GDHYILNGSK AFISGAGESD IYVVMCRTGG LGPKGISCIV VEKGTPGLSF GKKEKKVGWN SQPTRAVIFE DCAVPVANRI GSEGQGFLIA VRGLNGGRIN IASCSLGAAH ASVILTRDHL NVRKQFGEPL ASNQYLQFTL ADMATRLVAA RLMVRNAAVA LQEERKDAVA LCSMAKLFAT DECFAICNQA LQMHGGYGYL KDYAVQQYVR DSRVHQILEG SNEVMRILIS RSLLQE (1-415 aa encoded by B C001964)
Target Information
This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACAD-8; Activator-recruited cofactor 42 kDa component; Acyl-CoA dehydrogenase family member 8; acyl-CoA dehydrogenase family, member 8; acyl-Coenzyme A dehydrogenase family, member 8; ARC42; IBDH; Isobutyryl-CoA dehydrogenase, mitochondrial
Gene Aliases: 2310016C19Rik; ACAD-8; ACAD8; AI786953; ARC42; IBD; RGD1564209
UniProt ID: (Human) Q9UKU7, (Mouse) Q9D7B6
Entrez Gene ID: (Human) 27034, (Rat) 367196, (Mouse) 66948
fatty-acyl-CoA binding
acyl-CoA dehydrogenase activity
electron carrier activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
short-branched-chain-acyl-CoA dehydrogenase activity
very-long-chain-acyl-CoA dehydrogenase activity
4-methyloctanoyl-CoA dehydrogenase activity
naphthyl-2-methyl-succinyl-CoA dehydrogenase activity
2-methylhexanoyl-CoA dehydrogenase activity
propionyl-CoA dehydrogenase activity
thiol-driven fumarate reductase activity
coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity
coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity
coenzyme F420-dependent 2,4-dinitrophenol reductase activity
medium-chain-acyl-CoA dehydrogenase activity
dehydrogenase
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