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7TM Antibodies
ACKR2, Atypical Chemokine Receptor 2 Polyclonal Antibody
FIGURE: 1 / 2
ACKR2, Atypical Chemokine Receptor 2 Antibody (7TM0314N) in ICC/IF
Immunocytochemical validation of the Atypical Chemokine Receptor 2 in transfected HEK293 cells. Native HEK293 cells (MOCK) or HEK293 cells stably expressing the Atypical Chemokine Receptor 2 (ACKR2) were immunocytochemical stained with the phosphorylation-independent anti-ACKR2 antibody (7TM0314N-WB) at a dilution of 1:200.
Product Details
7TM0314N
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide presents the carboxyl - terminal tail of human ACKR2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Atypical chemokine receptor 2; C-C chemokine receptor D6; CC-chemokine-binding receptor JAB61; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; Chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; Chemokine-binding protein 2; Chemokine-binding protein D6
Gene Aliases: ACKR2; CCBP2; CCR10; CCR9; CMKBR9; D6; hD6
UniProt ID: (Human) O00590
Entrez Gene ID: (Human) 1238
Performance Guarantee
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