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ACSL5 Antibody (TA811884) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ACSL5 (RC213380, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ACSL5. Positive lysates LY404321 (100 µg) and LC404321 (20 µg) can be purchased separately from OriGene.
Product Details
TA811884
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI1C6
Immunogen
Human recombinant protein fragment corresponding to amino acids 104-620 of human ACSL5 produced in E.coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Arachidonate--CoA ligase; FACL5 for fatty acid coenzyme A ligase 5; fatty acid coenzyme A ligase 5; fatty acid Coenzyme A ligase, long chain 5; fatty-acid-Coenzyme A ligase, long-chain 5; HGNC:16526; LACS 5; Long-chain acyl-CoA synthetase 5; long-chain fatty acid coenzyme A ligase 5; Long-chain-fatty-acid--CoA ligase 5
Gene Aliases: 1700030F05Rik; ACS2; ACS5; ACSL5; FACL5; UNQ633/PRO1250
UniProt ID: (Human) Q9ULC5, (Mouse) Q8JZR0
Entrez Gene ID: (Human) 51703, (Mouse) 433256
long-chain fatty acid metabolic process
long-chain fatty-acyl-CoA biosynthetic process
lipid metabolic process
fatty acid metabolic process
metabolic process
phospholipid biosynthetic process
positive regulation of plasma membrane long-chain fatty acid transport
positive regulation of triglyceride biosynthetic process
fatty acid transport
positive regulation of fatty acid beta-oxidation
regulation of extrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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