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Product Details
13537-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACTL7B Fusion Protein Ag4460 (1-415 aa encoded by BC033789)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MATRNSPMP LGTAQGDPGE AGTRPGPDAS LRDTGAATQL KMKPRKVHKI KAVIIDLGSQ YCKCGYAGEP RPTYFISSTV GKRCPEAADA GDTRKWTLVG HELLNTEAPL KLVNPLKHGI VVDWDCVQDI WEYIFRTAMK ILPEEHAVLV SDPPLSPSSN REKYAELMFE TFGIPAMHVT SQSLLSIYSY GKTSGLVVES GHGVSHVVPI SEGDVLPGLT SRADYAGGDL TNYLMQLLNE AGHAFTDDHL HIIEHIKKKC CYAAFLPEEE LGLVPEELRV DYELPDGKLI TIGQERFRCS EMLFQPSLAG STQPGLPELT AACLGRCQDT GFKEEMAANV LLCGGCTMLD GFPERFQREL SLLCPGDSPA VAAAPERKTS VWTGGSILAS LQAFQQLWVS KEEFEERGSV AIYSKC (1-415 aa encoded by B C033789)
Target Information
The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: actin-like 7-beta; actin-like 7B; Actin-like protein 7B; Actin-like-7-beta; MGC151192; MGC151194; RP11-3J11.2; t-actin 1; T-actin-1; testis tissue sperm-binding protein Li 43a; Testis-specific actin-1
Gene Aliases: ACTL7B; Tact1
UniProt ID: (Human) Q9Y614, (Mouse) Q9QY83, (Rat) Q4QR76
Entrez Gene ID: (Human) 10880, (Mouse) 11471, (Rat) 313183
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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