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Product Details
15127-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ALADIN Fusion Protein Ag7211 (226-546 aa encoded by BC000659)
Conjugate
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SLSTRPSSG CAQVLSHPGH TPVTSLAWAP SGGRLLSASP VDAAIRVWDV STETCVPLPW FRGGGVTNLL WSPDGSKILA TTPSAVFRVW EAQMWTCERW PTLSGRCQTG CWSPDGSRLL FTVLGEPLIY SLSFPERCGE GKGCVGGAKS ATIVADLSET TIQTPDGEER LGGEAHSMVW DPSGERLAVL MKGKPRVQDG KPVILLFRTR NSPVFELLPC GIIQGEPGAQ PQLITFHPSF NKGALLSVGW STGRIAHIPL YFVNAQFPRF SPVLGRAQEP PAGGGGSIHD LPLFTETSPT SAPWDPLPGP PPVLPHSPHS HL (226-546 aa encoded by BC000659)
Target Information
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: achalasia, adrenocortical insufficiency, alacrimia; Adracalin; Aladin; Allgrove, triple-A
Gene Aliases: AAA; AAAS; AAASb; ADRACALA; ADRACALIN; ALADIN; D030041N15Rik; GL003
UniProt ID: (Human) Q9NRG9, (Mouse) P58742
Entrez Gene ID: (Human) 8086, (Mouse) 223921
mRNA export from nucleus
tRNA export from nucleus
nucleocytoplasmic transport
mitotic nuclear envelope disassembly
learning
fertilization
regulation of glucose transport
protein transport
viral process
protein sumoylation
viral transcription
gene silencing by RNA
regulation of nucleocytoplasmic transport
intracellular transport of virus
regulation of cellular response to heat
transport
mRNA transport
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