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Invitrogen
ALDH1A1 Recombinant Rabbit Monoclonal Antibody (SY11-02)
FIGURE: 1 / 4
ALDH1A1 Antibody (MA5-41107) in IHC (P)
Immunohistochemistry (Paraffin) analysis of ALDH1A1 in paraffin-embedded human kidney tissue. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes.The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with ALDH1A1 Recombinant Monoclonal Antibody (Product # MA5-41107) at a dilution of 1:... View More
Product Details
MA5-41107
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SY11-02
Immunogen
Synthetic peptide within human ALDH1A1 aa 300-360
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 0.05% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2898861
Target Information
ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-deoxyglucosone dehydrogenase; acetaldehyde dehydrogenase 1; alcohol dehydrogenase family 1, subfamily A1; alcohol dehydrogenase family 1, subfamily A2; aldehyde dehydrogenase 1 family, member A1; Aldehyde dehydrogenase 1 soluble; aldehyde dehydrogenase 1, liver cytosolic (class 1); aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase 1, subfamily A1; Aldehyde dehydrogenase 1A1; aldehyde dehydrogenase 2; Aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase family 1, member A1; aldehyde dehydrogenase family 1, subfamily A1; Aldehyde dehydrogenase, cytosolic; aldehyde dehydrogenase, liver cytosolic; ALDH class 1; ALDH-E1; ALHDII; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; epididymis secretory sperm binding protein Li53e; MGC2318; RALDH 1; ralDH1; Retinal dehydrogenase 1; retinaldehyde dehydrogenase 1
Gene Aliases: Ahd-2; Ahd2; ALDC; Aldh; ALDH-E1; ALDH1; ALDH11; ALDH1A1; Aldh1a2; Aldh2; E1; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1
UniProt ID: (Human) P00352, (Mouse) P24549, (Rat) P51647
Entrez Gene ID: (Human) 216, (Mouse) 11668, (Rat) 24188
retinal dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
GTPase activator activity
androgen binding
benzaldehyde dehydrogenase (NAD+) activity
3-chloroallyl aldehyde dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
identical protein binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
ethanol oxidation
cellular aldehyde metabolic process
retinol metabolic process
positive regulation of GTPase activity
fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate
optic cup morphogenesis involved in camera-type eye development
retinoic acid biosynthetic process
response to oxidative stress
metabolic process
response to drug
retinoic acid metabolic process
9-cis-retinoic acid biosynthetic process
9-cis-retinoic acid metabolic process
positive regulation of apoptotic process
response to ethanol
embryonic eye morphogenesis
protein homotetramerization
oxidation-reduction process
kidney development
liver development
midgut development
response to organic cyclic compound
response to estradiol
response to retinoic acid
estrous cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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