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Product Details
PA5-110968
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human AMID. Recombinant protein control fragment (Product #RP-105802).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2856379
Product Specific Information
Immunogen sequence: MLVDMKDSFH HNVAALRASV ETGFAKKTFI SYSVTFKDNF RQGLVVGIDL KNQMVLLQGG EALPFSHLIL ATGSTGPFPG KFNEVSSQQA AIQAYEDMVR QVQRSRFIVV VGGGSAGVEM AAEIKTEYPE KEVTLIHSQV ALAD
Target Information
The p53 tumor suppressor protein induces cell cycle arrest or apoptosis in response to cellular stresses. PRG3 (p53-responsive gene 3), is induced specifically under p53-dependent apoptotic conditions in human colon cancer cells. PRG3 has significant homology to bacterial oxidoreductases and the apoptosis-inducing factor, AIF. Unlike AIF, PRG3 localizes in the cytoplasm and its ectopic expression induces apoptosis. The PRG3 gene is thus a novel p53 target gene in a p53-dependent apoptosis pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMID; apoptosis-inducing factor (AIF)-homologous mitochondrion-associated inducer of death; apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; apoptosis-inducing factor, mitochondrion-associated, 2; Ferroptosis suppressor protein 1; FSP1; MBP2; MBPH; MGC126662; MGC141971; p53-responsive gene 3 protein; RP11-367H5.2
Gene Aliases: AIFM2; AMID; PRG3
UniProt ID: (Human) Q9BRQ8
Entrez Gene ID: (Human) 84883
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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