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Product Details
MA1-91374
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
AP2g 6E4/4
Immunogen
Bacterial AP-2a/AP-2g fusion protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
IgG fraction
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2199433
Product Specific Information
MA1-91374 detects AP2 gamma from mouse, human samples.
Target Information
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating enhancer-binding protein 2 gamma; AP-2.2; AP2-gamma; estrogen receptor factor 1; stimulated by retinoic acid gene 2; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); Transcription factor ERF-1
Gene Aliases: AA409384; Ap-2.2; AP2-GAMMA; AP2gamma; ERF1; hAP-2g; Stra2; Tcfap2c; TFAP2C; TFAP2G
UniProt ID: (Human) Q92754, (Mouse) Q61312
Entrez Gene ID: (Human) 7022, (Mouse) 21420
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein dimerization activity
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell-cell signaling
male gonad development
regulation of gene expression, epigenetic
regulation of cell proliferation
positive regulation of transcription from RNA polymerase II promoter
trophectodermal cell differentiation
hair follicle development
keratinocyte development
transcription, DNA-templated
regulation of transcription, DNA-templated
stem cell population maintenance
forebrain neuron fate commitment
cerebral cortex development
cell differentiation
germ-line stem cell population maintenance
somatic stem cell population maintenance
skin development
regulation of epidermis development
sebaceous gland development
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
epithelial cell proliferation involved in mammary gland duct elongation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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