Product References
Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway.
International journal of molecular medicine
Yoon JS,Kim SS,Ha J,Kang I,Choe W
PA1-054 was used in Western Blotting to show that CypB levels regulates 3T3-L1 adipocyte differentiation via mTOR signaling pathway.
Sun Jan 01 00:00:00 EST 2023
Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway.
International journal of molecular medicine
Yoon JS,Kim SS,Ha J,Kang I,Choe W
PA1-054 was used in Western Blotting to show that CypB levels regulates 3T3-L1 adipocyte differentiation via mTOR signaling pathway.
Sun Jan 01 00:00:00 EST 2023
PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction.
Cells
He Y,Zhang R,Yu L,Zahr T,Li X,Kim TW,Qiang L
PA1-054 was used in Western Blot to suggest pathogenic implications of adipocyte PPARγ acetylation, contributing to metabolic dysfunction in aging and thus posing as a potential therapeutic target.
Thu May 18 00:00:00 EDT 2023
PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction.
Cells
He Y,Zhang R,Yu L,Zahr T,Li X,Kim TW,Qiang L
PA1-054 was used in Western Blot to suggest pathogenic implications of adipocyte PPARγ acetylation, contributing to metabolic dysfunction in aging and thus posing as a potential therapeutic target.
Thu May 18 00:00:00 EDT 2023
Uncoupling Lipid Synthesis from Adipocyte Development.
Biomedicines
Wan Q,Calhoun C,Zahr T,Qiang L
PA1-054 was used in Western Blotting to suggest that lipid synthesis and storage are not the defining features of adipocytes and raise the possibility of uncoupling lipid synthesis from adipocyte development to achieve smaller and healthier adipocytes for the treatment of obesity and related disorders.
Sun Apr 09 00:00:00 EDT 2023
Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity.
Life metabolism
Aaron N,Zahr T,He Y,Yu L,Mayfield B,Pajvani UB,Qiang L
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Thu Dec 01 00:00:00 EST 2022
Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis.
Molecular metabolism
Frei IC,Weissenberger D,Ritz D,Heusermann W,Colombi M,Shimobayashi M,Hall MN
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Immunohistochemistry
Tue Nov 01 00:00:00 EDT 2022
Adipose mTORC2 is essential for sensory innervation in white adipose tissue and whole-body energy homeostasis.
Molecular metabolism
Frei IC,Weissenberger D,Ritz D,Heusermann W,Colombi M,Shimobayashi M,Hall MN
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Immunohistochemistry
Tue Nov 01 00:00:00 EDT 2022
Selective targeting of visceral adiposity by polycation nanomedicine.
Nature nanotechnology
Wan Q,Huang B,Li T,Xiao Y,He Y,Du W,Wang BZ,Dakin GF,Rosenbaum M,Goncalves MD,Chen S,Leong KW,Qiang L
PA1-054 was used in Western Blotting to highlight a strategy to target visceral adiposity and suggests that cationic nanomaterials could be exploited for treating metabolic diseases.
Thu Dec 01 00:00:00 EST 2022
Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells.
Cell metabolism
Li J,Li E,Czepielewski RS,Chi J,Guo X,Han YH,Wang D,Wang L,Hu B,Dawes B,Jacobs C,Tenen D,Lin SJ,Lee B,Morris D,Tobias A,Randolph GJ,Cohen P,Tsai L,Rosen ED
PA1-054 was used in Western Blotting to establish a link between adipose tissue lymphatics and adipocytes.
Tue Jul 06 00:00:00 EDT 2021
KAT8, lysine acetyltransferase 8, is required for adipocyte differentiation in vitro.
Biochimica et biophysica acta. Molecular basis of disease
Burrell JA,Stephens JM
PA1-054 was used in Western Blotting to demonstrate that KAT8 is required for adipocyte differentiation.
Tue Jun 01 00:00:00 EDT 2021
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
eLife
Aaron N,Kraakman MJ,Zhou Q,Liu Q,Costa S,Yang J,Liu L,Yu L,Wang L,He Y,Fan L,Hirakawa H,Ding L,Lo J,Wang W,Zhao B,Guo E,Sun L,Rosen CJ,Qiang L
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Tue Jun 22 00:00:00 EDT 2021
Adipsin promotes bone marrow adiposity by priming mesenchymal stem cells.
eLife
Aaron N,Kraakman MJ,Zhou Q,Liu Q,Costa S,Yang J,Liu L,Yu L,Wang L,He Y,Fan L,Hirakawa H,Ding L,Lo J,Wang W,Zhao B,Guo E,Sun L,Rosen CJ,Qiang L
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Tue Jun 22 00:00:00 EDT 2021
Bacillus subtilis Spore-Trained Dendritic Cells Enhance the Generation of Memory T Cells via ICAM1.
Cells
Lin J,Huang L,Li Y,Zhang P,Yu Q,Yang Q
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Tue Aug 31 00:00:00 EDT 2021
Generation of two multipotent mesenchymal progenitor cell lines capable of osteogenic, mature osteocyte, adipogenic, and chondrogenic differentiation.
Scientific reports
Prideaux M,Wright CS,Noonan ML,Yi X,Clinkenbeard EL,Mevel E,Wheeler JA,Byers S,Wijenayaka AR,Gronthos S,Sankar U,White KE,Atkins GJ,Thompson WR
PA1-054 was used in Western Blot to develop two mesenchymal progenitor cell (MPC) lines, MPC1 and MPC2, generated from bone marrow of male C57BL/6 mice.
Fri Nov 19 00:00:00 EST 2021
The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
Proceedings of the National Academy of Sciences of the United States of America
Gunn KH,Roberts BS,Wang F,Strauss JD,Borgnia MJ,Egelman EH,Neher SB
PA1-054 was used in Immunocytochemistry-immunoflourescence to present a cryo-EM reconstruction of a helical LPL oligomer at 3.8-Å resolution.
Tue May 12 00:00:00 EDT 2020
The structure of helical lipoprotein lipase reveals an unexpected twist in lipase storage.
Proceedings of the National Academy of Sciences of the United States of America
Gunn KH,Roberts BS,Wang F,Strauss JD,Borgnia MJ,Egelman EH,Neher SB
PA1-054 was used in Immunocytochemistry-immunoflourescence to present a cryo-EM reconstruction of a helical LPL oligomer at 3.8-Å resolution.
Tue May 12 00:00:00 EDT 2020
Mitochondrial Pyruvate Carriers are not Required for Adipogenesis but are Regulated by High-Fat Feeding in Brown Adipose Tissue.
Obesity (Silver Spring, Md.)
Burrell JA,Richard AJ,King WT,Stephens JM
PA1-054 was used in Western Blot to assess the role of mitochondrial pyruvate carriers (MPCs) in adipocyte development in vitro and determine whether MPCs are regulated in vivo by high-fat feeding in male and female C57BL/6J mice.
Sat Feb 01 00:00:00 EST 2020
β-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Sen B,Paradise CR,Xie Z,Sankaran J,Uzer G,Styner M,Meyer M,Dudakovic A,van Wijnen AJ,Rubin J
PA1-054 was used in Western Blotting to indicate that regulating EZH2 activity is key to β-catenin's effects on BMSCs to preserve multipotentiality.
Mon Jun 01 00:00:00 EDT 2020
Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.
Pharmacology research & perspectives
Ma O,Le T,Talbott G,HoangThao Nguyen T,Ha D,Ho L
PA1-054 was used in Western Blot to discover that Sirt3 plays a role in modulating adipogenesis and adiponectin/adipdokine expression.
Tue Dec 01 00:00:00 EST 2020
Sirt3 regulates adipogenesis and adipokine secretion via its enzymatic activity.
Pharmacology research & perspectives
Ma O,Le T,Talbott G,HoangThao Nguyen T,Ha D,Ho L
PA1-054 was used in Western Blot to discover that Sirt3 plays a role in modulating adipogenesis and adiponectin/adipdokine expression.
Tue Dec 01 00:00:00 EST 2020
Adiponectin accounts for gender differences in hepatocellular carcinoma incidence.
The Journal of experimental medicine
Manieri E,Herrera-Melle L,Mora A,Tomás-Loba A,Leiva-Vega L,Fernández DI,Rodríguez E,Morán L,Hernández-Cosido L,Torres JL,Seoane LM,Cubero FJ,Marcos M,Sabio G
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Mon May 06 00:00:00 EDT 2019
PPARγ deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects.
The Journal of clinical investigation
Kraakman MJ,Liu Q,Postigo-Fernandez J,Ji R,Kon N,Larrea D,Namwanje M,Fan L,Chan M,Area-Gomez E,Fu W,Creusot RJ,Qiang L
PA1-054 was used in Western Blotting to show that targeted PPARγ mutations result in constitutive deacetylation, increased energy expenditure and protect from visceral adiposity and diet-induced obesity by augmenting brown remodelling of white adipose tissues.
Fri Jun 01 00:00:00 EDT 2018
LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage.
Bone
Thompson WR,Yen SS,Uzer G,Xie Z,Sen B,Styner M,Burridge K,Rubin J
PA1-054 was used in Western Blotting to show on and off GTP exchangers work through RhoA to influence MSC fate and responses to static and dynamic physical factors in the microenvironment.
Thu Feb 01 00:00:00 EST 2018
Distinct adipocyte progenitor cells are associated with regional phenotypes of perivascular aortic fat in mice.
Molecular metabolism
Tran KV,Fitzgibbons T,Min SY,DeSouza T,Corvera S
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Thu Mar 01 00:00:00 EST 2018
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.
JCI insight
Obata Y,Kita S,Koyama Y,Fukuda S,Takeda H,Takahashi M,Fujishima Y,Nagao H,Masuda S,Tanaka Y,Nakamura Y,Nishizawa H,Funahashi T,Ranscht B,Izumi Y,Bamba T,Fukusaki E,Hanayama R,Shimada S,Maeda N,Shimomura I
PA1-054 was used in Western Blotting to demonstrate that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides.
Thu Apr 19 00:00:00 EDT 2018
Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release.
JCI insight
Obata Y,Kita S,Koyama Y,Fukuda S,Takeda H,Takahashi M,Fujishima Y,Nagao H,Masuda S,Tanaka Y,Nakamura Y,Nishizawa H,Funahashi T,Ranscht B,Izumi Y,Bamba T,Fukusaki E,Hanayama R,Shimada S,Maeda N,Shimomura I
PA1-054 was used in Western Blotting to demonstrate that the adiponectin/T-cadherin system enhances exosome biogenesis and secretion, leading to the decrease of cellular ceramides.
Thu Apr 19 00:00:00 EDT 2018
Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue.
PloS one
Jager M,Lee MJ,Li C,Farmer SR,Fried SK,Layne MD
PA1-054 was used in Western Blotting to investigate the role of aortic carboxypeptidase-like protein on adipose progenitor differentiation in the context of adipose tissue fibrosis.
Tue Dec 11 00:00:00 EST 2018
Characterisation of adipocyte-derived extracellular vesicle subtypes identifies distinct protein and lipid signatures for large and small extracellular vesicles.
Journal of extracellular vesicles
Durcin M,Fleury A,Taillebois E,Hilairet G,Krupova Z,Henry C,Truchet S,Trötzmüller M,Köfeler H,Mabilleau G,Hue O,Andriantsitohaina R,Martin P,Le Lay S
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Thu Oct 01 00:00:00 EDT 2020
Adipocytes play an etiological role in the podocytopathy of high-fat diet-fed rats.
The Journal of endocrinology
Chen JY,Jian DY,Lien CC,Lin YT,Ting CH,Chen LK,Hsu TC,Huang HM,Wu YT,Kuan TT,Chao YW,Wu LY,Huang SW,Juan CC
PA1054 was used in blocking or activating experiment to elucidate the relationship between obesity and chronic kidney disease
Tue Nov 01 00:00:00 EDT 2016
Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue.
Scientific reports
Ronkainen J,Huusko TJ,Soininen R,Mondini E,Cinti F,Mäkelä KA,Kovalainen M,Herzig KH,Järvelin MR,Sebert S,Savolainen MJ,Salonurmi T
PA1-054 was used in western blot to elucidate the relationship among FTO, IRX3 and fat metabolism.
Wed Mar 18 00:00:00 EDT 2015
Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells.
Stem cells (Dayton, Ohio)
Thompson WR,Guilluy C,Xie Z,Sen B,Brobst KE,Yen SS,Uzer G,Styner M,Case N,Burridge K,Rubin J
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Fri Nov 01 00:00:00 EDT 2013
T-cadherin is essential for adiponectin-mediated revascularization.
The Journal of biological chemistry
Parker-Duffen JL,Nakamura K,Silver M,Kikuchi R,Tigges U,Yoshida S,Denzel MS,Ranscht B,Walsh K
PA1-054 was used in immunohistochemistry to study the role of T-cadherin in the mechanism by which adiponectin promotes revascularization
Fri Aug 23 00:00:00 EDT 2013
Activation of AMPK-Sirt1 pathway by telmisartan in white adipose tissue: A possible link to anti-metabolic effects.
European journal of pharmacology
Shiota A,Shimabukuro M,Fukuda D,Soeki T,Sato H,Uematsu E,Hirata Y,Kurobe H,Sakaue H,Nakaya Y,Masuzaki H,Sata M
PA1-054 was used in western blot to study the activation of the AMPK-Sirt1 pathway in white adipose tissue by telmisartan
Fri Oct 05 00:00:00 EDT 2012
Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice.
Cardiovascular diabetology
Shiota A,Shimabukuro M,Fukuda D,Soeki T,Sato H,Uematsu E,Hirata Y,Kurobe H,Maeda N,Sakaue H,Masuzaki H,Shimomura I,Sata M
PA1-054 was used in western blot to study the role of the AMPK/SIRT1 pathway in the mechanism by which telmisartan improves skeletal muscle insulin-sensitivity in obese mice
Thu Nov 08 00:00:00 EST 2012
The activities of lysyl hydroxylase 3 (LH3) regulate the amount and oligomerization status of adiponectin.
PloS one
Ruotsalainen H,Risteli M,Wang C,Wang Y,Karppinen M,Bergmann U,Kvist AP,Pospiech H,Herzig KH,Myllylä R
PA1-054 was used in western blot to study the modulation of adiponectin levels and oligimerization by lysyl hydroxylase-3
Tue Jun 11 00:00:00 EDT 2013
St. John's Wort inhibits insulin signaling in murine and human adipocytes.
Biochimica et biophysica acta
Richard AJ,Amini ZJ,Ribnicky DM,Stephens JM
PA1-054 was used in western blot to study the inhibition of human and murine adipocyte insulin signaling by extracts of St John's Wort
Sun Apr 01 00:00:00 EDT 2012
STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system.
Obesity (Silver Spring, Md.)
Stewart WC,Pearcy LA,Floyd ZE,Stephens JM
PA1-054 was used in western blot to investigate the effect of STAT5A on adipogenesis
Thu Sep 01 00:00:00 EDT 2011
STAT5A expression in Swiss 3T3 cells promotes adipogenesis in vivo in an athymic mice model system.
Obesity (Silver Spring, Md.)
Stewart WC,Pearcy LA,Floyd ZE,Stephens JM
PA1-054 was used in western blot to investigate the effect of STAT5A on adipogenesis
Thu Sep 01 00:00:00 EDT 2011
N-linked glycosylation of mouse adiponectin.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Tanaka M,Fukuhara A,Shimomura I
PA1-054 was used in western blot to characterize mouse adiponectin in terms of post-translational modification
Fri Jul 01 00:00:00 EDT 2011
T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion.
Islets
Tyrberg B,Miles P,Azizian KT,Denzel MS,Nieves ML,Monosov EZ,Levine F,Ranscht B
PA1-054 was used in Immunohistochemistry to suggest that synaptic vesicle membranes are predominantly retrieved via clathrin-independent endocytosis mediated by formin-dependent actin assembly.
Fri Jun 01 00:00:00 EDT 2012
Comparative epigenomic analysis of murine and human adipogenesis.
Cell
Mikkelsen TS,Xu Z,Zhang X,Wang L,Gimble JM,Lander ES,Rosen ED
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Fri Oct 01 00:00:00 EDT 2010
Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation.
Biochemical and biophysical research communications
Ishihara K,Takahashi I,Tsuchiya Y,Hasegawa M,Kamemura K
PA1-054 was used in western blot to investigate the effect of glycosylation on adipogenesis
Fri Jul 30 00:00:00 EDT 2010
Adiponectin deficiency limits tumor vascularization in the MMTV-PyV-mT mouse model of mammary cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Denzel MS,Hebbard LW,Shostak G,Shapiro L,Cardiff RD,Ranscht B
PA1-054 was used in immunocytochemistry to investigate the effect of adiponectin on tumor angiogenesis in in a mammary cancer mouse model.
Fri May 15 00:00:00 EDT 2009
T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model.
Cancer research
Hebbard LW,Garlatti M,Young LJ,Cardiff RD,Oshima RG,Ranscht B
PA1-054 was used in immunohistochemistry to study the role of T-cadherin in angiogenesis.
Sat Mar 01 00:00:00 EST 2008
TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity.
Molecular and cellular biology
Bezy O,Vernochet C,Gesta S,Farmer SR,Kahn CR
PA1-054 was used in western blot to study the role of Tribbles homologue 3 TRB3 during adipogenesis.
Mon Oct 01 00:00:00 EDT 2007
The cannabinoid CB1 receptor antagonist rimonabant (SR141716) inhibits cell proliferation and increases markers of adipocyte maturation in cultured mouse 3T3 F442A preadipocytes.
Molecular pharmacology
Gary-Bobo M,Elachouri G,Scatton B,Le Fur G,Oury-Donat F,Bensaid M
PA1-054 was used in western blot to study the effect of rimonabant on endocrine function of mouse 3T3 F442A preadipocytes
Wed Feb 01 00:00:00 EST 2006
JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.
The Journal of biological chemistry
Nguyen MT,Satoh H,Favelyukis S,Babendure JL,Imamura T,Sbodio JI,Zalevsky J,Dahiyat BI,Chi NW,Olefsky JM
PA1-054 was used in western blot to investigate the role of JNK and tumor necrosis factor-alpha in free fatty acid-induced insulin resistance in 3T3-L1 adipocytes.
Fri Oct 21 00:00:00 EDT 2005
Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.
The Journal of biological chemistry
Guilherme A,Soriano NA,Furcinitti PS,Czech MP
PA1-054 was used in western blot to investigate the function of EHD1 and EHBP1 in perinuclear localization of GLUT4.
Fri Sep 17 00:00:00 EDT 2004
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats.
Proceedings of the National Academy of Sciences of the United States of America
Shklyaev S,Aslanidi G,Tennant M,Prima V,Kohlbrenner E,Kroutov V,Campbell-Thompson M,Crawford J,Shek EW,Scarpace PJ,Zolotukhin S
Published figure using Adiponectin polyclonal antibody (Product # PA1-054) in Western Blot
Tue Nov 25 00:00:00 EST 2003