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AgRP Antibody (PA5-47895) in IHC (P)
Immunohistochemical analysis of AgRP in immersion fixed paraffin-embedded sections of human brain (hippocampus). Samples were incubated in AgRP polyclonal antibody (Product # PA5-47895) using a dilution of 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic . Tissue was stained using the Anti-Goa... View More
Product Details
PA5-47895
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant human AgRP/ART Ala21-Thr132
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610536
Product Specific Information
In Western blots, approximately 40% cross-reactivity with recombinant mouse AgRP/ART is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Agouti-related protein (AgRP), also called agouti-related peptide, is a neuropeptide produced in the brain by the AgRP/NPY neuron. In humans, the agouti-related peptide is encoded by the AGRP gene. This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: agouti related protein homolog; Agouti-related protein
Gene Aliases: AGRP; AGRT; ART; ASIP2
UniProt ID: (Human) O00253
Entrez Gene ID: (Human) 181
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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