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Invitrogen
Apelin Receptor Recombinant Rabbit Monoclonal Antibody (5H5L9)
FIGURE: 1 / 3
Apelin Receptor Antibody (702069) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized HeLa cells for detection of endogenous APLNR using Anti-APLNR Recombinant Rabbit Monoclonal Antibody (Product # 702069, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localizat... View More
Product Details
702069
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
5H5L9
Immunogen
Peptides corresponding to Human APLNR (aa 6-20, 52-66)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2633058
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, Horse and Dog
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
APLNR (Apelin Receptor) is a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: angiotensin II receptor-like 1; Angiotensin receptor-like 1; Apelin receptor; APJ (apelin) receptor; APJ receptor; G protein-coupled receptor APJ; G-protein coupled receptor APJ; G-protein coupled receptor HG11; HG11 orphan receptor; MSR
Gene Aliases: AGTRL1; APJ; APJR; APLNR; HG11; msr/apj
UniProt ID: (Human) P35414, (Mouse) Q9WV08
Entrez Gene ID: (Human) 187, (Mouse) 23796
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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