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Invitrogen
Apolipoprotein H Monoclonal Antibody (4A2F8H12)
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 6
Apolipoprotein H Antibody (MA5-29035) in ICC/IF
Immunofluorescence analysis of Beta-2-glycoprotein 1 was performed using 70% confluent log phase Hep G2, Hep G2 treated with PTI (1X for 4hrs) and PC-3 cells treated with PTI (1X for 4hrs). The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Apolipoprotein H... View More
Product Details
MA5-29035
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4A2F8H12
Immunogen
Recombinant Human APOH protein (Met1-Cys345)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2784970
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human APOH/B2G1.
Target Information
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2GPI; Activated protein C-binding protein; Anticardiolipin cofactor; APC inhibitor; Apo-H; Apolipoprotein H; apolipoprotein H (beta-2-glycoprotein I); B2GPI; beta(2)GPI; Beta-2-glycoprotein 1; Beta-2-glycoprotein I
Gene Aliases: APOH; B2G1; B2GP1; BG
UniProt ID: (Human) P02749
Entrez Gene ID: (Human) 350
negative regulation of endothelial cell proliferation
platelet degranulation
triglyceride metabolic process
aging
blood coagulation, intrinsic pathway
negative regulation of endothelial cell migration
positive regulation of triglyceride catabolic process
negative regulation of angiogenesis
positive regulation of blood coagulation
negative regulation of blood coagulation
organ regeneration
plasminogen activation
negative regulation of myeloid cell apoptotic process
response to triglyceride
triglyceride transport
negative regulation of smooth muscle cell apoptotic process
positive regulation of lipoprotein lipase activity
regulation of fibrinolysis
negative regulation of fibrinolysis
negative regulation of respiratory burst
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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