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Product Details
13490-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
B3GALT4 Fusion Protein Ag4312 (83-378 aa encoded by BC032574)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: NLNQRNAIR ASWGGLREAR GLRVQTLFLL GEPNAQHPVW GSQGSDLASE SAAQGDILQA AFQDSYRNLT LKTLSGLNWA EKHCPMARYV LKTDDDVYVN VPELVSELVL RGGRWGQWER STEPQREAEQ EGGQVLHSEE VPLLYLGRVH WRVNPSRTPG GRHRVSEEQW PHTWGPFPPY ASGTGYVLSA SAVQLILKVA SRAPLLPLED VFVGVSARRG GLAPTQCVKL AGATHYPLDR CCYGKFLLTS HRLDPWKMQE AWKLVGGSDG ERTAPFCSWF QGVLGILRCR AIAWLQS (83-378 aa encoded by BC032574)
Target Information
This gene is a member of the beta-1, 3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: b3Gal-T4; Beta-1,3-galactosyltransferase 4; Beta-1,3-GalTase 4; beta-3-galactosyltransferase 4; beta3Gal-T4; beta3GalT4; GAL-T2; Ganglioside galactosyltransferase; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4; UDP-Gal:betaGlcNAc beta 13-galactosyltransferase polypeptide 4; UDP-galactose:beta-N-acetyl-galactosamine-beta-1,3-galactosyltransferase
Gene Aliases: B3GALT4; BETA3GALT4; Gal-T2; GALT2; GALT4
UniProt ID: (Human) O96024, (Mouse) Q9Z0F0
Entrez Gene ID: (Human) 8705, (Mouse) 54218, (Rat) 171079
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