Product References
Native Size-Exclusion Chromatography-Based Mass Spectrometry Reveals New Components of the Early Heat Shock Protein 90 Inhibition Response Among Limited Global Changes.
Molecular & cellular proteomics : MCP
Samant RS,Batista S,Larance M,Ozer B,Milton CI,Bludau I,Wu E,Biggins L,Andrews S,Hervieu A,Johnston HE,Al-Lazikhani B,Lamond AI,Clarke PA,Workman P
Wed Feb 01 00:00:00 EST 2023
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1.
bioRxiv : the preprint server for biology
Lin H,Sandkuhler S,Dunlea C,King DH,Johnson GVW
Thu Feb 09 00:00:00 EST 2023
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1.
bioRxiv : the preprint server for biology
Lin H,Sandkuhler S,Dunlea C,King DH,Johnson GVW
Thu Feb 09 00:00:00 EST 2023
BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1.
bioRxiv : the preprint server for biology
Lin H,Sandkuhler S,Dunlea C,King DH,Johnson GVW
Thu Feb 09 00:00:00 EST 2023
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Xian Z,Tian J,Zhao Y,Yi Y,Li C,Han J,Zhang Y,Wang Y,Wang L,Liu S,Pan C,Liu C,Wang D,Meng J,Tang X,Wang F,Liang A
Thu Jun 01 00:00:00 EDT 2023
Z-Disk-Associated Plectin (Isoform 1d): Spatial Arrangement, Interaction Partners, and Role in Filamin C Homeostasis.
Cells
Winter L,Staszewska-Daca I,Zittrich S,Elhamine F,Zrelski MM,Schmidt K,Fischer I,Jüngst C,Schauss A,Goldmann WH,Stehle R,Wiche G
Wed Apr 26 00:00:00 EDT 2023
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Neuron
Sheehan PW,Nadarajah CJ,Kanan MF,Patterson JN,Novotny B,Lawrence JH,King MW,Brase L,Inman CE,Yuede CM,Lee J,Patel TK,Harari O,Benitez BA,Davis AA,Musiek ES
Wed Aug 02 00:00:00 EDT 2023
An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Neuron
Sheehan PW,Nadarajah CJ,Kanan MF,Patterson JN,Novotny B,Lawrence JH,King MW,Brase L,Inman CE,Yuede CM,Lee J,Patel TK,Harari O,Benitez BA,Davis AA,Musiek ES
Wed Aug 02 00:00:00 EDT 2023
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Nature nanotechnology
Chen X,Wang S,Chen Y,Xin H,Zhang S,Wu D,Xue Y,Zha M,Li H,Li K,Gu Z,Wei W,Ping Y
Tue Aug 01 00:00:00 EDT 2023
Proteotoxic stress-induced autophagy is regulated by the NRF2 pathway via extracellular vesicles.
Cell stress & chaperones
Okusha Y,Murshid A,Calderwood SK
Wed Mar 01 00:00:00 EST 2023
BAG3 promotes autophagy and suppresses NLRP3 inflammasome activation in Parkinson's disease.
Annals of translational medicine
Ying ZM,Lv QK,Yao XY,Dong AQ,Yang YP,Cao YL,Wang F,Gong AP,Liu CF
Tue Nov 01 00:00:00 EDT 2022
Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module.
iScience
Patel S,Kumar S,Baldan S,Hesin A,Yaglom J,Sherman MY
Fri May 20 00:00:00 EDT 2022
Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC-overexpressing triple-negative breast cancer.
Cell chemical biology
Kunder R,Velyunskiy M,Dunne SF,Cho BK,Kanojia D,Begg L,Orriols AM,Fleming-Trujillo E,Vadlamani P,Vialichka A,Bolin R,Perrino JN,Roth D,Clutter MR,Zielinski-Mozny NA,Goo YA,Cristofanilli M,Mendillo ML,Vassilopoulos A,Horiuchi D
Thu Mar 17 00:00:00 EDT 2022
Proximity proteomics of C9orf72 dipeptide repeat proteins identifies molecular chaperones as modifiers of poly-GA aggregation.
Acta neuropathologica communications
Liu F,Morderer D,Wren MC,Vettleson-Trutza SA,Wang Y,Rabichow BE,Salemi MR,Phinney BS,Oskarsson B,Dickson DW,Rossoll W
Mon Feb 14 00:00:00 EST 2022
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang C,Tang Q,Xia H,Xu H,Bi F
Sat Jan 01 00:00:00 EST 2022
PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhang C,Tang Q,Xia H,Xu H,Bi F
Sat Jan 01 00:00:00 EST 2022
An Important Role for RPRD1B in the Heat Shock Response.
Molecular and cellular biology
Cugusi S,Bajpe PK,Mitter R,Patel H,Stewart A,Svejstrup JQ
Thu Oct 20 00:00:00 EDT 2022
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis.
Journal of physiology and biochemistry
Lu X,Zhang J,Xue P,Wang Q,Wang X,Sun Y,Cui Z
Sun May 01 00:00:00 EDT 2022
MicroRNA-570 targets the HSP chaperone network, increases proteotoxic stress and inhibits mammary tumor cell migration.
Scientific reports
Okusha Y,Guerrero-Gimenez ME,Lang BJ,Borges TJ,Stevenson MA,Truman AW,Calderwood SK
Fri Sep 16 00:00:00 EDT 2022
Hgs Deficiency Caused Restrictive Cardiomyopathy via Disrupting Proteostasis.
International journal of biological sciences
Li Z,Wang T,Xin C,Song Y,Kong J,Xu J,Liu Q,Teng Y,Hou N,Cheng X,Yang G,Liu W,Zhou B,Zhang Y,Yang X,Wang J
Fri Dec 23 00:00:00 EST 2022
Hgs Deficiency Caused Restrictive Cardiomyopathy via Disrupting Proteostasis.
International journal of biological sciences
Li Z,Wang T,Xin C,Song Y,Kong J,Xu J,Liu Q,Teng Y,Hou N,Cheng X,Yang G,Liu W,Zhou B,Zhang Y,Yang X,Wang J
Fri Dec 23 00:00:00 EST 2022
Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles.
Cell communication and signaling : CCS
Van den Broek B,Wuyts C,Sisto A,Pintelon I,Timmermans JP,Somers V,Timmerman V,Hellings N,Irobi J
Thu May 05 00:00:00 EDT 2022
Triangulating variation in the population to define mechanisms for precision management of genetic disease.
Structure (London, England : 1993)
Wang C,Anglès F,Balch WE
Thu Aug 04 00:00:00 EDT 2022
Therapeutic induction of Bcl2-associated athanogene 3-mediated autophagy in idiopathic pulmonary fibrosis.
Clinical and translational medicine
Chillappagari S,Schwarz J,Kesireddy V,Knoell J,Korfei M,Hoetzenecker K,Schmitz ML,Behl C,Bellusci S,Guenther A,Mahavadi P
Fri Jul 01 00:00:00 EDT 2022
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Journal of cellular biochemistry
Martin TG,Delligatti CE,Muntu NA,Stachowski-Doll MJ,Kirk JA
Sat Jan 01 00:00:00 EST 2022
Pharmacological inhibition of BAG3-HSP70 with the proposed cancer therapeutic JG-98 is toxic for cardiomyocytes.
Journal of cellular biochemistry
Martin TG,Delligatti CE,Muntu NA,Stachowski-Doll MJ,Kirk JA
Sat Jan 01 00:00:00 EST 2022
BAG3 Alleviates Atherosclerosis by Inhibiting Endothelial-to-Mesenchymal Transition via Autophagy Activation.
Genes
Diao H,Wu K,Lan D,Wang D,Zhao J,Huang B,Shao X,Wang R,Tan H,Tang X,Yan M,Zhang Y
Tue Jul 26 00:00:00 EDT 2022
Missense mutations in small muscle protein X-linked (SMPX) cause distal myopathy with protein inclusions.
Acta neuropathologica
Johari M,Sarparanta J,Vihola A,Jonson PH,Savarese M,Jokela M,Torella A,Piluso G,Said E,Vella N,Cauchi M,Magot A,Magri F,Mauri E,Kornblum C,Reimann J,Stojkovic T,Romero NB,Luque H,Huovinen S,Lahermo P,Donner K,Comi GP,Nigro V,Hackman P,Udd B
Sun Aug 01 00:00:00 EDT 2021
Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction.
Brain : a journal of neurology
Van Lent J,Verstraelen P,Asselbergh B,Adriaenssens E,Mateiu L,Verbist C,De Winter V,Eggermont K,Van Den Bosch L,De Vos WH,Timmerman V
Sat Sep 04 00:00:00 EDT 2021
A weakened interface in the P182L variant of HSP27 associated with severe Charcot-Marie-Tooth neuropathy causes aberrant binding to interacting proteins.
The EMBO journal
Alderson TR,Adriaenssens E,Asselbergh B,Pritišanac I,Van Lent J,Gastall HY,Wälti MA,Louis JM,Timmerman V,Baldwin AJ,Lp Benesch J
Thu Apr 15 00:00:00 EDT 2021
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
American journal of cancer research
Lu J,Liu SY,Zhang J,Yang GM,Gao GB,Yu NN,Li YP,Li YX,Ma ZQ,Wang Y,Lu CH
Sat Aug 07 00:00:00 EDT 2021
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Nature communications
Martin TG,Myers VD,Dubey P,Dubey S,Perez E,Moravec CS,Willis MS,Feldman AM,Kirk JA
Wed May 19 00:00:00 EDT 2021
Cardiomyocyte contractile impairment in heart failure results from reduced BAG3-mediated sarcomeric protein turnover.
Nature communications
Martin TG,Myers VD,Dubey P,Dubey S,Perez E,Moravec CS,Willis MS,Feldman AM,Kirk JA
Wed May 19 00:00:00 EDT 2021
Neuromodulation of BAG co-chaperones by HIV-1 viral proteins and H2O2: implications for HIV-associated neurological disorders.
Cell death discovery
Duggan MR,Mohseni Ahooyi T,Parikh V,Khalili K
Fri Mar 26 00:00:00 EDT 2021
Neuromodulation of BAG co-chaperones by HIV-1 viral proteins and H2O2: implications for HIV-associated neurological disorders.
Cell death discovery
Duggan MR,Mohseni Ahooyi T,Parikh V,Khalili K
Fri Mar 26 00:00:00 EDT 2021
Myoblast mechanotransduction and myotube morphology is dependent on BAG3 regulation of YAP and TAZ.
Biomaterials
Günay KA,Silver JS,Chang TL,Bednarski OJ,Bannister KL,Rogowski CJ,Olwin BB,Anseth KS
Fri Oct 01 00:00:00 EDT 2021
Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling.
Translational research : the journal of laboratory and clinical medicine
Jia P,Wu N,Yang H,Guo Y,Guo X,Sun Y
Thu Jul 01 00:00:00 EDT 2021
Hsp22 Deficiency Induces Age-Dependent Cardiac Dilation and Dysfunction by Impairing Autophagy, Metabolism, and Oxidative Response.
Antioxidants (Basel, Switzerland)
Wu W,Sun X,Shi X,Lai L,Wang C,Xie M,Qin G,Qiu H
Wed Sep 29 00:00:00 EDT 2021
BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease.
American journal of physiology. Heart and circulatory physiology
Martin TG,Tawfik S,Moravec CS,Pak TR,Kirk JA
Tue Jun 01 00:00:00 EDT 2021
BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease.
American journal of physiology. Heart and circulatory physiology
Martin TG,Tawfik S,Moravec CS,Pak TR,Kirk JA
Tue Jun 01 00:00:00 EDT 2021
A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction.
European journal of medicinal chemistry
Wang Z,Song T,Guo Z,Uwituze LB,Guo Y,Zhang H,Wang H,Zhang X,Pan H,Ji T,Yin F,Zhou S,Dai J,Zhang Z
Thu Aug 05 00:00:00 EDT 2021
Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy.
Nature communications
Kimura K,Ooms A,Graf-Riesen K,Kuppusamy M,Unger A,Schuld J,Daerr J,Lother A,Geisen C,Hein L,Takahashi S,Li G,Röll W,Bloch W,van der Ven PFM,Linke WA,Wu SM,Huesgen PF,Höhfeld J,Fürst DO,Fleischmann BK,Hesse M
Fri Jun 11 00:00:00 EDT 2021
Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy.
Nature communications
Kimura K,Ooms A,Graf-Riesen K,Kuppusamy M,Unger A,Schuld J,Daerr J,Lother A,Geisen C,Hein L,Takahashi S,Li G,Röll W,Bloch W,van der Ven PFM,Linke WA,Wu SM,Huesgen PF,Höhfeld J,Fürst DO,Fleischmann BK,Hesse M
Fri Jun 11 00:00:00 EDT 2021
TRIM28 functions as a negative regulator of aggresome formation.
Autophagy
Chang J,Hwang HJ,Kim B,Choi YG,Park J,Park Y,Lee BS,Park H,Yoon MJ,Woo JS,Kim C,Park MS,Lee JB,Kim YK
Wed Dec 01 00:00:00 EST 2021
Isoform-specific functions of synaptopodin-2 variants in cytoskeleton stabilization and autophagy regulation in muscle under mechanical stress.
Experimental cell research
Lohanadan K,Molt S,Dierck F,van der Ven PFM,Frey N,Höhfeld J,Fürst DO
Mon Nov 15 00:00:00 EST 2021
Isoform-specific functions of synaptopodin-2 variants in cytoskeleton stabilization and autophagy regulation in muscle under mechanical stress.
Experimental cell research
Lohanadan K,Molt S,Dierck F,van der Ven PFM,Frey N,Höhfeld J,Fürst DO
Mon Nov 15 00:00:00 EST 2021
Locus specific epigenetic modalities of random allelic expression imbalance.
Nature communications
Marion-Poll L,Forêt B,Zielinski D,Massip F,Attia M,Carter AC,Syx L,Chang HY,Gendrel AV,Heard E
Thu Sep 09 00:00:00 EDT 2021
Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.
Communications biology
Reimann L,Schwäble AN,Fricke AL,Mühlhäuser WWD,Leber Y,Lohanadan K,Puchinger MG,Schäuble S,Faessler E,Wiese H,Reichenbach C,Knapp B,Peikert CD,Drepper F,Hahn U,Kreutz C,van der Ven PFM,Radziwill G,Djinović-Carugo K,Fürst DO,Warscheid B
Fri May 22 00:00:00 EDT 2020
An integrative correlation of myopathology, phenotype and genotype in late onset Pompe disease.
Neuropathology and applied neurobiology
Kulessa M,Weyer-Menkhoff I,Viergutz L,Kornblum C,Claeys KG,Schneider I,Plöckinger U,Young P,Boentert M,Vielhaber S,Mawrin C,Bergmann M,Weis J,Ziagaki A,Stenzel W,Deschauer M,Nolte D,Hahn A,Schoser B,Schänzer A
Mon Jun 01 00:00:00 EDT 2020
Absence of Sac2/INPP5F enhances the phenotype of a Parkinson's disease mutation of synaptojanin 1.
Proceedings of the National Academy of Sciences of the United States of America
Cao M,Park D,Wu Y,De Camilli P
Tue Jun 02 00:00:00 EDT 2020
BAG3 Proteomic Signature under Proteostasis Stress.
Cells
Hiebel C,Stürner E,Hoffmeister M,Tascher G,Schwarz M,Nagel H,Behrends C,Münch C,Behl C
Wed Nov 04 00:00:00 EST 2020
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes.
Scientific reports
Adriaenssens E,Tedesco B,Mediani L,Asselbergh B,Crippa V,Antoniani F,Carra S,Poletti A,Timmerman V
Fri May 29 00:00:00 EDT 2020
BAG3 Pro209 mutants associated with myopathy and neuropathy relocate chaperones of the CASA-complex to aggresomes.
Scientific reports
Adriaenssens E,Tedesco B,Mediani L,Asselbergh B,Crippa V,Antoniani F,Carra S,Poletti A,Timmerman V
Fri May 29 00:00:00 EDT 2020
Sprint and Strength Training Modulates Autophagy and Proteostasis in Aging Sprinters.
Medicine and science in sports and exercise
Hentilä J,Hulmi JJ,Laakkonen EK,Ahtiainen JP,Suominen H,Korhonen MT
Tue Sep 01 00:00:00 EDT 2020
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation.
Acta neuropathologica communications
Schuld J,Orfanos Z,Chevessier F,Eggers B,Heil L,Uszkoreit J,Unger A,Kirfel G,van der Ven PFM,Marcus K,Linke WA,Clemen CS,Schröder R,Fürst DO
Fri Sep 04 00:00:00 EDT 2020
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation.
Acta neuropathologica communications
Schuld J,Orfanos Z,Chevessier F,Eggers B,Heil L,Uszkoreit J,Unger A,Kirfel G,van der Ven PFM,Marcus K,Linke WA,Clemen CS,Schröder R,Fürst DO
Fri Sep 04 00:00:00 EDT 2020
Induction of BIS Protein During Astroglial and Fibrotic Scar Formation After Mitochondrial Toxin-Mediated Neuronal Injury in Rats.
Molecular neurobiology
Riew TR,Kim S,Jin X,Kim HL,Yoo K,Seo SB,Lee JH,Lee MY
Tue Sep 01 00:00:00 EDT 2020
The lncRNA LOC102549805 (U1) modulates neurotoxicity of HIV-1 Tat protein.
Cell death & disease
Torkzaban B,Natarajaseenivasan K,Mohseni Ahooyi T,Shekarabi M,Amini S,Langford TD,Khalili K
Thu Oct 08 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
Host BAG3 Is Degraded by Pseudorabies Virus pUL56 C-Terminal 181L-185L and Plays a Negative Regulation Role during Viral Lytic Infection.
International journal of molecular sciences
Lyu C,Li WD,Wang SW,Peng JM,Yang YB,Tian ZJ,Cai XH
Wed Apr 29 00:00:00 EDT 2020
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
Nature neuroscience
Fu H,Possenti A,Freer R,Nakano Y,Hernandez Villegas NC,Tang M,Cauhy PVM,Lassus BA,Chen S,Fowler SL,Figueroa HY,Huey ED,Johnson GVW,Vendruscolo M,Duff KE
Tue Jan 01 00:00:00 EST 2019
A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology.
Nature neuroscience
Fu H,Possenti A,Freer R,Nakano Y,Hernandez Villegas NC,Tang M,Cauhy PVM,Lassus BA,Chen S,Fowler SL,Figueroa HY,Huey ED,Johnson GVW,Vendruscolo M,Duff KE
Tue Jan 01 00:00:00 EST 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes.
Journal of cellular physiology
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Prado FJ,Shanmughapriya S,Rajan S,Tomar D,Tahrir FG,Gupta MK,Knezevic T,Merabova N,Kontos CD,McClung JM,Klotman PE,Madesh M,Khalili K,Feldman AM
Mon Apr 01 00:00:00 EDT 2019
Imbalances in protein homeostasis caused by mutant desmin.
Neuropathology and applied neurobiology
Winter L,Unger A,Berwanger C,Spörrer M,Türk M,Chevessier F,Strucksberg KH,Schlötzer-Schrehardt U,Wittig I,Goldmann WH,Marcus K,Linke WA,Clemen CS,Schröder R
Thu Aug 01 00:00:00 EDT 2019
Imbalances in protein homeostasis caused by mutant desmin.
Neuropathology and applied neurobiology
Winter L,Unger A,Berwanger C,Spörrer M,Türk M,Chevessier F,Strucksberg KH,Schlötzer-Schrehardt U,Wittig I,Goldmann WH,Marcus K,Linke WA,Clemen CS,Schröder R
Thu Aug 01 00:00:00 EDT 2019
BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes.
Autophagy
Ji C,Tang M,Zeidler C,Höhfeld J,Johnson GV
Mon Jul 01 00:00:00 EDT 2019
BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes.
Autophagy
Ji C,Tang M,Zeidler C,Höhfeld J,Johnson GV
Mon Jul 01 00:00:00 EDT 2019
The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy.
Biochimica et biophysica acta. Molecular cell research
Klimek C,Jahnke R,Wördehoff J,Kathage B,Stadel D,Behrends C,Hergovich A,Höhfeld J
Tue Oct 01 00:00:00 EDT 2019
Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells.
Cell death & disease
Mohseni Ahooyi T,Torkzaban B,Shekarabi M,Tahrir FG,Decoppet EA,Cotto B,Langford D,Amini S,Khalili K
Mon Jun 17 00:00:00 EDT 2019
Perturbation of synapsins homeostasis through HIV-1 Tat-mediated suppression of BAG3 in primary neuronal cells.
Cell death & disease
Mohseni Ahooyi T,Torkzaban B,Shekarabi M,Tahrir FG,Decoppet EA,Cotto B,Langford D,Amini S,Khalili K
Mon Jun 17 00:00:00 EDT 2019
Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes.
Scientific reports
Ghasemi Tahrir F,Gupta M,Myers V,Gordon J,Cheung JY,Feldman AM,Khalili K
Tue May 21 00:00:00 EDT 2019
Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes.
Scientific reports
Ghasemi Tahrir F,Gupta M,Myers V,Gordon J,Cheung JY,Feldman AM,Khalili K
Tue May 21 00:00:00 EDT 2019
Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress.
Redox biology
Chakraborty D,Felzen V,Hiebel C,Stürner E,Perumal N,Manicam C,Sehn E,Grus F,Wolfrum U,Behl C
Sat Jun 01 00:00:00 EDT 2019
Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress.
Redox biology
Chakraborty D,Felzen V,Hiebel C,Stürner E,Perumal N,Manicam C,Sehn E,Grus F,Wolfrum U,Behl C
Sat Jun 01 00:00:00 EDT 2019
Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes.
JCI insight
McDermott-Roe C,Lv W,Maximova T,Wada S,Bukowy J,Marquez M,Lai S,Shehu A,Benjamin I,Geurts A,Musunuru K
Thu Nov 14 00:00:00 EST 2019
Investigation of a dilated cardiomyopathy-associated variant in BAG3 using genome-edited iPSC-derived cardiomyocytes.
JCI insight
McDermott-Roe C,Lv W,Maximova T,Wada S,Bukowy J,Marquez M,Lai S,Shehu A,Benjamin I,Geurts A,Musunuru K
Thu Nov 14 00:00:00 EST 2019
Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection.
Journal of internal medicine
Palucci I,Matic I,Falasca L,Minerva M,Maulucci G,De Spirito M,Petruccioli E,Goletti D,Rossin F,Piacentini M,Delogu G
Thu Mar 01 00:00:00 EST 2018
Transglutaminase type 2 plays a key role in the pathogenesis of Mycobacterium tuberculosis infection.
Journal of internal medicine
Palucci I,Matic I,Falasca L,Minerva M,Maulucci G,De Spirito M,Petruccioli E,Goletti D,Rossin F,Piacentini M,Delogu G
Thu Mar 01 00:00:00 EST 2018
Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.
Journal of cellular physiology
Myers VD,Tomar D,Madesh M,Wang J,Song J,Zhang XQ,Gupta MK,Tahrir FG,Gordon J,McClung JM,Kontos CD,Khalili K,Cheung JY,Feldman AM
Sat Sep 01 00:00:00 EDT 2018
Haplo-insufficiency of Bcl2-associated athanogene 3 in mice results in progressive left ventricular dysfunction, β-adrenergic insensitivity, and increased apoptosis.
Journal of cellular physiology
Myers VD,Tomar D,Madesh M,Wang J,Song J,Zhang XQ,Gupta MK,Tahrir FG,Gordon J,McClung JM,Kontos CD,Khalili K,Cheung JY,Feldman AM
Sat Sep 01 00:00:00 EDT 2018
Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Shanmughapriya S,Ahooyi TM,Knezevic T,Gupta MK,Kontos CD,McClung JM,Madesh M,Gordon J,Feldman AM,Cheung JY,Khalili K
Thu Feb 01 00:00:00 EST 2018
Dysregulation of mitochondrial bioenergetics and quality control by HIV-1 Tat in cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Shanmughapriya S,Ahooyi TM,Knezevic T,Gupta MK,Kontos CD,McClung JM,Madesh M,Gordon J,Feldman AM,Cheung JY,Khalili K
Thu Feb 01 00:00:00 EST 2018
Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy.
Disease models & mechanisms
Jokl EJ,Hughes GL,Cracknell T,Pownall ME,Blanco G
Fri Jul 06 00:00:00 EDT 2018
Transcriptional upregulation of Bag3, a chaperone-assisted selective autophagy factor, in animal models of KY-deficient hereditary myopathy.
Disease models & mechanisms
Jokl EJ,Hughes GL,Cracknell T,Pownall ME,Blanco G
Fri Jul 06 00:00:00 EDT 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner.
Neurobiology of aging
Tang M,Ji C,Pallo S,Rahman I,Johnson GVW
Thu Mar 01 00:00:00 EST 2018
Comparison of hepatic transcriptome profiling between acute liver injury and acute liver failure induced by acetaminophen in mice.
Toxicology letters
Li C,Ming Y,Hong W,Tang Y,Lei X,Li X,Mao Y
Thu Feb 01 00:00:00 EST 2018
Comparison of hepatic transcriptome profiling between acute liver injury and acute liver failure induced by acetaminophen in mice.
Toxicology letters
Li C,Ming Y,Hong W,Tang Y,Lei X,Li X,Mao Y
Thu Feb 01 00:00:00 EST 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
Dysregulated autophagy in restrictive cardiomyopathy due to Pro209Leu mutation in BAG3.
Molecular genetics and metabolism
Schänzer A,Rupp S,Gräf S,Zengeler D,Jux C,Akintürk H,Gulatz L,Mazhari N,Acker T,Van Coster R,Garvalov BK,Hahn A
Thu Mar 01 00:00:00 EST 2018
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
Biochemical and biophysical research communications
Clemen CS,Winter L,Strucksberg KH,Berwanger C,Türk M,Kornblum C,Florin A,Aguilar-Pimentel JA,Amarie OV,Becker L,Garrett L,Hans W,Moreth K,Neff F,Pingen L,Rathkolb B,Rácz I,Rozman J,Treise I,Fuchs H,Gailus-Durner V,de Angelis MH,Vorgerd M,Eichinger L,Schröder R
Tue Sep 18 00:00:00 EDT 2018
The heterozygous R155C VCP mutation: Toxic in humans! Harmless in mice?
Biochemical and biophysical research communications
Clemen CS,Winter L,Strucksberg KH,Berwanger C,Türk M,Kornblum C,Florin A,Aguilar-Pimentel JA,Amarie OV,Becker L,Garrett L,Hans W,Moreth K,Neff F,Pingen L,Rathkolb B,Rácz I,Rozman J,Treise I,Fuchs H,Gailus-Durner V,de Angelis MH,Vorgerd M,Eichinger L,Schröder R
Tue Sep 18 00:00:00 EDT 2018
Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy.
The Journal of biological chemistry
Hutt DM,Mishra SK,Roth DM,Larsen MB,Angles F,Frizzell RA,Balch WE
Fri Aug 31 00:00:00 EDT 2018
Silencing of the Hsp70-specific nucleotide-exchange factor BAG3 corrects the F508del-CFTR variant by restoring autophagy.
The Journal of biological chemistry
Hutt DM,Mishra SK,Roth DM,Larsen MB,Angles F,Frizzell RA,Balch WE
Fri Aug 31 00:00:00 EDT 2018
PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.
Autophagy
Ma K,Fu W,Tang M,Zhang C,Hou T,Li R,Lu X,Wang Y,Zhou J,Li X,Zhang L,Wang L,Zhao Y,Zhu WG
Sat Mar 04 00:00:00 EST 2017
PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment.
Autophagy
Ma K,Fu W,Tang M,Zhang C,Hou T,Li R,Lu X,Wang Y,Zhou J,Li X,Zhang L,Wang L,Zhao Y,Zhu WG
Sat Mar 04 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress.
PLoS pathogens
Liang J,Sagum CA,Bedford MT,Sidhu SS,Sudol M,Han Z,Harty RN
Sun Jan 01 00:00:00 EST 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
Evidence for the Role of BAG3 in Mitochondrial Quality Control in Cardiomyocytes.
Journal of cellular physiology
Tahrir FG,Knezevic T,Gupta MK,Gordon J,Cheung JY,Feldman AM,Khalili K
Sat Apr 01 00:00:00 EDT 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy.
Neurobiology of aging
Cao YL,Yang YP,Mao CJ,Zhang XQ,Wang CT,Yang J,Lv DJ,Wang F,Hu LF,Liu CF
Fri Dec 01 00:00:00 EST 2017
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Biochimica et biophysica acta. Molecular cell research
Kathage B,Gehlert S,Ulbricht A,Lüdecke L,Tapia VE,Orfanos Z,Wenzel D,Bloch W,Volkmer R,Fleischmann BK,Fürst DO,Höhfeld J
Sun Jan 01 00:00:00 EST 2017
The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Biochimica et biophysica acta. Molecular cell research
Kathage B,Gehlert S,Ulbricht A,Lüdecke L,Tapia VE,Orfanos Z,Wenzel D,Bloch W,Volkmer R,Fleischmann BK,Fürst DO,Höhfeld J
Sun Jan 01 00:00:00 EST 2017
Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.
Frontiers in neuroscience
Sebastiani A,Gölz C,Sebastiani PG,Bobkiewicz W,Behl C,Mittmann T,Thal SC,Engelhard K
Wed Sep 30 00:00:00 EDT 2020
Sequestosome 1 Deficiency Delays, but Does Not Prevent Brain Damage Formation Following Acute Brain Injury in Adult Mice.
Frontiers in neuroscience
Sebastiani A,Gölz C,Sebastiani PG,Bobkiewicz W,Behl C,Mittmann T,Thal SC,Engelhard K
Wed Sep 30 00:00:00 EDT 2020
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
HSPB8 Promotes the Fusion of Autophagosome and Lysosome during Autophagy in Diabetic Neurons.
International journal of medical sciences
Li XC,Hu QK,Chen L,Liu SY,Su S,Tao H,Zhang LN,Sun T,He LJ
Fri Jul 20 00:00:00 EDT 2018
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
JCI insight
Judge LM,Perez-Bermejo JA,Truong A,Ribeiro AJ,Yoo JC,Jensen CL,Mandegar MA,Huebsch N,Kaake RM,So PL,Srivastava D,Pruitt BL,Krogan NJ,Conklin BR
Thu Jul 20 00:00:00 EDT 2017
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
JCI insight
Judge LM,Perez-Bermejo JA,Truong A,Ribeiro AJ,Yoo JC,Jensen CL,Mandegar MA,Huebsch N,Kaake RM,So PL,Srivastava D,Pruitt BL,Krogan NJ,Conklin BR
Thu Jul 20 00:00:00 EDT 2017
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
JCI insight
Judge LM,Perez-Bermejo JA,Truong A,Ribeiro AJ,Yoo JC,Jensen CL,Mandegar MA,Huebsch N,Kaake RM,So PL,Srivastava D,Pruitt BL,Krogan NJ,Conklin BR
Thu Jul 20 00:00:00 EDT 2017
Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex.
Nature communications
Park J,Park Y,Ryu I,Choi MH,Lee HJ,Oh N,Kim K,Kim KM,Choe J,Lee C,Baik JH,Kim YK
Wed Jun 07 00:00:00 EDT 2017
Misfolded polypeptides are selectively recognized and transported toward aggresomes by a CED complex.
Nature communications
Park J,Park Y,Ryu I,Choi MH,Lee HJ,Oh N,Kim K,Kim KM,Choe J,Lee C,Baik JH,Kim YK
Wed Jun 07 00:00:00 EDT 2017
Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing.
Biomaterials
Wang BK,Yu XF,Wang JH,Li ZB,Li PH,Wang H,Song L,Chu PK,Li C
Mon Feb 01 00:00:00 EST 2016
Gold-nanorods-siRNA nanoplex for improved photothermal therapy by gene silencing.
Biomaterials
Wang BK,Yu XF,Wang JH,Li ZB,Li PH,Wang H,Song L,Chu PK,Li C
Mon Feb 01 00:00:00 EST 2016
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Adeno-associated Virus Serotype 9 - Driven Expression of BAG3 Improves Left Ventricular Function in Murine Hearts with Left Ventricular Dysfunction Secondary to a Myocardial Infarction.
JACC. Basic to translational science
Knezevic T,Myers VD,Su F,Wang J,Song J,Zhang XQ,Gao E,Gao G,Muniswamy M,Gupta MK,Gordon J,Weiner KN,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Dec 01 00:00:00 EST 2016
Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.
Biochimica et biophysica acta
Diaz-Hidalgo L,Altuntas S,Rossin F,D'Eletto M,Marsella C,Farrace MG,Falasca L,Antonioli M,Fimia GM,Piacentini M
Mon Aug 01 00:00:00 EDT 2016
Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.
Biochimica et biophysica acta
Diaz-Hidalgo L,Altuntas S,Rossin F,D'Eletto M,Marsella C,Farrace MG,Falasca L,Antonioli M,Fimia GM,Piacentini M
Mon Aug 01 00:00:00 EDT 2016
Diagnostically important muscle pathology in DNAJB6 mutated LGMD1D.
Acta neuropathologica communications
Sandell S,Huovinen S,Palmio J,Raheem O,Lindfors M,Zhao F,Haapasalo H,Udd B
Fri Feb 05 00:00:00 EST 2016
Diagnostically important muscle pathology in DNAJB6 mutated LGMD1D.
Acta neuropathologica communications
Sandell S,Huovinen S,Palmio J,Raheem O,Lindfors M,Zhao F,Haapasalo H,Udd B
Fri Feb 05 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Bcl-2-associated athanogene 3 protects the heart from ischemia/reperfusion injury.
JCI insight
Su F,Myers VD,Knezevic T,Wang J,Gao E,Madesh M,Tahrir FG,Gupta MK,Gordon J,Rabinowitz J,Ramsey FV,Tilley DG,Khalili K,Cheung JY,Feldman AM
Thu Nov 17 00:00:00 EST 2016
Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy.
Neurology
Ghaoui R,Palmio J,Brewer J,Lek M,Needham M,Evilä A,Hackman P,Jonson PH,Penttilä S,Vihola A,Huovinen S,Lindfors M,Davis RL,Waddell L,Kaur S,Yiannikas C,North K,Clarke N,MacArthur DG,Sue CM,Udd B
Tue Jan 26 00:00:00 EST 2016
BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes.
Journal of molecular and cellular cardiology
Feldman AM,Gordon J,Wang J,Song J,Zhang XQ,Myers VD,Tilley DG,Gao E,Hoffman NE,Tomar D,Madesh M,Rabinowitz J,Koch WJ,Su F,Khalili K,Cheung JY
Tue Mar 01 00:00:00 EST 2016
Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle.
Autophagy
Ulbricht A,Gehlert S,Leciejewski B,Schiffer T,Bloch W,Höhfeld J
Mon Mar 07 00:00:00 EST 2016
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
WW domain of BAG3 is required for the induction of autophagy in glioma cells.
Journal of cellular physiology
Merabova N,Sariyer IK,Saribas AS,Knezevic T,Gordon J,Turco MC,Rosati A,Weaver M,Landry J,Khalili K
Wed Apr 01 00:00:00 EDT 2015
BAG3 facilitates the clearance of endogenous tau in primary neurons.
Neurobiology of aging
Lei Z,Brizzee C,Johnson GV
Thu Jan 01 00:00:00 EST 2015
BAG3 facilitates the clearance of endogenous tau in primary neurons.
Neurobiology of aging
Lei Z,Brizzee C,Johnson GV
Thu Jan 01 00:00:00 EST 2015
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
Human molecular genetics
Chevessier F,Schuld J,Orfanos Z,Plank AC,Wolf L,Maerkens A,Unger A,Schlötzer-Schrehardt U,Kley RA,Von Hörsten S,Marcus K,Linke WA,Vorgerd M,van der Ven PF,Fürst DO,Schröder R
Sun Dec 20 00:00:00 EST 2015
Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.
Clinical and translational science
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Tilley DG,Gao E,Koch WJ,Rabinowitz J,Klotman PE,Khalili K,Feldman AM
Sat Aug 01 00:00:00 EDT 2015
Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3.
Clinical and translational science
Cheung JY,Gordon J,Wang J,Song J,Zhang XQ,Tilley DG,Gao E,Koch WJ,Rabinowitz J,Klotman PE,Khalili K,Feldman AM
Sat Aug 01 00:00:00 EDT 2015
The cleavage product of amyloid-β protein precursor sAβPPα modulates BAG3-dependent aggresome formation and enhances cellular proteasomal activity.
Journal of Alzheimer's disease : JAD
Renziehausen J,Hiebel C,Nagel H,Kundu A,Kins S,Kögel D,Behl C,Hajieva P
Mon Oct 26 00:00:00 EDT 2015
Chaperone molecules concentrate together with the ubiquitin-proteasome system inside particulate cytoplasmic structures: possible role in metabolism of misfolded proteins.
Histochemistry and cell biology
Vanoli A,Necchi V,Barozzi S,Manca R,Pecci A,Solcia E
Sat Aug 01 00:00:00 EDT 2015
Chaperone molecules concentrate together with the ubiquitin-proteasome system inside particulate cytoplasmic structures: possible role in metabolism of misfolded proteins.
Histochemistry and cell biology
Vanoli A,Necchi V,Barozzi S,Manca R,Pecci A,Solcia E
Sat Aug 01 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
Analysis of HDAC6 and BAG3-aggresome pathways in African swine fever viral factory formation.
Viruses
Muñoz-Moreno R,Barrado-Gil L,Galindo I,Alonso C
Wed Apr 08 00:00:00 EDT 2015
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.
Journal of cellular physiology
Feldman AM,Begay RL,Knezevic T,Myers VD,Slavov DB,Zhu W,Gowan K,Graw SL,Jones KL,Tilley DG,Coleman RC,Walinsky P,Cheung JY,Mestroni L,Khalili K,Taylor MR
Sat Nov 01 00:00:00 EDT 2014
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy.
Journal of cellular physiology
Feldman AM,Begay RL,Knezevic T,Myers VD,Slavov DB,Zhu W,Gowan K,Graw SL,Jones KL,Tilley DG,Coleman RC,Walinsky P,Cheung JY,Mestroni L,Khalili K,Taylor MR
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.
Molecular & cellular proteomics : MCP
Xue L,Wang P,Cao P,Zhu JK,Tao WA
Sat Nov 01 00:00:00 EDT 2014
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy.
Current biology : CB
Ulbricht A,Eppler FJ,Tapia VE,van der Ven PF,Hampe N,Hersch N,Vakeel P,Stadel D,Haas A,Saftig P,Behrends C,Fürst DO,Volkmer R,Hoffmann B,Kolanus W,Höhfeld J
Mon Mar 04 00:00:00 EST 2013
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes.
Journal of cell science
Xu Z,Graham K,Foote M,Liang F,Rizkallah R,Hurt M,Wang Y,Wu Y,Zhou Y
Sun Sep 15 00:00:00 EDT 2013
14-3-3 protein targets misfolded chaperone-associated proteins to aggresomes.
Journal of cell science
Xu Z,Graham K,Foote M,Liang F,Rizkallah R,Hurt M,Wang Y,Wu Y,Zhou Y
Sun Sep 15 00:00:00 EDT 2013
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
Mutations affecting the cytoplasmic functions of the co-chaperone DNAJB6 cause limb-girdle muscular dystrophy.
Nature genetics
Sarparanta J,Jonson PH,Golzio C,Sandell S,Luque H,Screen M,McDonald K,Stajich JM,Mahjneh I,Vihola A,Raheem O,Penttilä S,Lehtinen S,Huovinen S,Palmio J,Tasca G,Ricci E,Hackman P,Hauser M,Katsanis N,Udd B
Sun Feb 26 00:00:00 EST 2012
Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.
PloS one
Sariyer IK,Merabova N,Patel PK,Knezevic T,Rosati A,Turco MC,Khalili K
Tue Mar 05 00:00:00 EST 2013
Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.
PloS one
Sariyer IK,Merabova N,Patel PK,Knezevic T,Rosati A,Turco MC,Khalili K
Tue Mar 05 00:00:00 EST 2013
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins.
EMBO reports
Gamerdinger M,Kaya AM,Wolfrum U,Clement AM,Behl C
Tue Feb 01 00:00:00 EST 2011
BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.
The Journal of biological chemistry
Gentilella A,Khalili K
Fri Mar 18 00:00:00 EDT 2011
BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.
The Journal of biological chemistry
Gentilella A,Khalili K
Fri Mar 18 00:00:00 EDT 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells.
PloS one
Kettern N,Rogon C,Limmer A,Schild H,Höhfeld J
Thu Jan 20 00:00:00 EST 2011
Chaperone-assisted selective autophagy is essential for muscle maintenance.
Current biology : CB
Arndt V,Dick N,Tawo R,Dreiseidler M,Wenzel D,Hesse M,Fürst DO,Saftig P,Saint R,Fleischmann BK,Hoch M,Höhfeld J
Tue Jan 26 00:00:00 EST 2010
Chaperone-assisted selective autophagy is essential for muscle maintenance.
Current biology : CB
Arndt V,Dick N,Tawo R,Dreiseidler M,Wenzel D,Hesse M,Fürst DO,Saftig P,Saint R,Fleischmann BK,Hoch M,Höhfeld J
Tue Jan 26 00:00:00 EST 2010
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009
Autoregulation of co-chaperone BAG3 gene transcription.
Journal of cellular biochemistry
Gentilella A,Khalili K
Tue Dec 01 00:00:00 EST 2009
