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FIGURE: 1 / 1
BANK1 Antibody (PA5-87800) in WB
Western blot analysis of BANK1 in extracts of various cell lines. Samples were incubated with BANK1 Polyclonal antibody (Product # PA5-87800) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3s.
Product Details
PA5-87800
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 516-785 of human BANK1 (NP_0604054)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804419
Product Specific Information
Immunogen sequence: PVANAFQLER PHFTLPGTMV EGQMERSQNW GHPGVRQETG DEPKGEKEKK EEEKEQEEEE DPYTFAEIDD SEYDMILANL SIKKKTGSRS FIINRPPAPT PRPTSIPPKE ETTPYIAQVF QQKTARRQSD DDKFRGLPKK QDRARIESPA FSTLRGCLTD GQEELILLQE KVKNGKMSMD EALEKFKHWQ MGKSGLEMIQ QEKLRQLRDC IIGKRPEEEN VYNKLTIVHH PGGKETAHNE NKFYNVHFSN KLPARPQVEK EFGFCCKKDH; Positive Samples: B cells, Raji, U-87MG, A-549, 22Rv1, HepG2, Mouse liver, Rat liver
Target Information
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B-cell scaffold protein with ankyrin repeats; B-cell scaffold protein with ankyrin repeats 1 delta 2 transcript; Protein AVIEF
Gene Aliases: A530094C12Rik; AI451642; AVIEF; BANK; BANK1; LRRGT00104
UniProt ID: (Human) Q8NDB2, (Mouse) Q80VH0
Entrez Gene ID: (Human) 55024, (Rat) 365948, (Mouse) 242248
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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