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BBS7 Antibody (PA5-106343) in ICC/IF
Immunofluorescent analysis of BBS7 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and BBS7 polyclonal antibody (Product # PA5-106343) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-106343
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BBS7(Accession Q8IWZ6), corresponding to amino acid residues E399-A449.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854019
Product Specific Information
Antibody detects endogenous levels of total BBS7.
Target Information
BBS7, also named as BBS2L1, is a component of the BBSome complex which is required for ciliogenesis but is dispensable for centriolar satellite function. BBS7 is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 7 protein; Bardet-Biedl syndrome 7 protein homolog; BBS2-like 1; BBS2-like protein 1; BBSome complex member BBS7; FLJ10715
Gene Aliases: 8430406N16Rik; BBS2L1; BBS7
UniProt ID: (Human) Q8IWZ6, (Mouse) Q8K2G4
Entrez Gene ID: (Human) 55212, (Rat) 361930, (Mouse) 71492
eye development
heart looping
regulation of transcription from RNA polymerase II promoter
smoothened signaling pathway
determination of left/right symmetry
brain development
visual perception
protein localization
protein transport
melanosome transport
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
nonmotile primary cilium assembly
cilium assembly
fat cell differentiation
intracellular transport
digestive tract morphogenesis
pigment granule aggregation in cell center
palate development
limb development
cilium morphogenesis
heart development
biological_process
transport
cell projection organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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