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Product Details
PA5-22055
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 263 and 540 of BBS7 (Uniprot ID#Q8IWZ6)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11152691
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse liver.
Predicted reactivity: Mouse (93%), Rat (93%), Zebrafish (80%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
BBS7, also named as BBS2L1, is a component of the BBSome complex which is required for ciliogenesis but is dispensable for centriolar satellite function. BBS7 is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 7 protein; Bardet-Biedl syndrome 7 protein homolog; BBS2-like 1; BBS2-like protein 1; BBSome complex member BBS7; FLJ10715
Gene Aliases: 8430406N16Rik; BBS2L1; BBS7
UniProt ID: (Human) Q8IWZ6, (Mouse) Q8K2G4
Entrez Gene ID: (Human) 55212, (Mouse) 71492
eye development
heart looping
regulation of transcription from RNA polymerase II promoter
smoothened signaling pathway
determination of left/right symmetry
brain development
visual perception
protein localization
protein transport
melanosome transport
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
nonmotile primary cilium assembly
cilium assembly
fat cell differentiation
intracellular transport
digestive tract morphogenesis
pigment granule aggregation in cell center
palate development
limb development
cilium morphogenesis
transport
heart development
cell projection organization
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