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Product Details
PA5-21470
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 243 of BHMT (Uniprot ID#Q93088)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11156024
Product Specific Information
Recommended positive controls: HepG2, mouse liver.
Predicted reactivity: Mouse (95%), Rat (93%), Zebrafish (82%), Xenopus laevis (87%), Pig (95%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Betaine--homocysteine S-methyltransferase 1; epididymis secretory sperm binding protein Li 61p
Gene Aliases: BHMT; BHMT1; HEL-S-61p
UniProt ID: (Human) Q93088, (Mouse) O35490
Entrez Gene ID: (Human) 635, (Mouse) 12116
sulfur amino acid metabolic process
protein methylation
amino-acid betaine metabolic process
amino-acid betaine catabolic process
choline catabolic process
S-adenosylmethionine metabolic process
regulation of homocysteine metabolic process
L-methionine salvage
methionine biosynthetic process
methylation
S-methylmethionine cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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