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Product Details
16461-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BPNT1 Fusion Protein Ag9523 (1-325 aa encoded by BC017801)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASSNTVLM RLVASAYSIA QKAGMIVRRV IAEGDLGIVE KTCATDLQTK ADRLAQMSIC SSLARKFPKL TIIGEEDLPS EEVDQELIED SQWEEILKQP CPSQYSAIKE EDLVVWVDPL DGTKEYTEGL LDNVTVLIGI AYEGKAIAGV INQPYYNYEA GPDAVLGRTI WGVLGLGAFG FQLKEVPAGK HIITTTRSHS NKLVTDCVAA MNPDAVLRVG GVGNKIIQLI EGKASAYVFA SPGCKKWDTC APEVILHAVG GKLTDIHGNV LQYHKDVSHR TWPKPDFFRA QFFLESHSCF SRNFKNVSTP IKNIYDVIIY AYETDL (1-325 aa encoded by B C017801)
Target Information
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 3'(2'),5'-bisphosphate nucleotidase 1; 3'-phosphoadenosine 5'-phosphate phosphatase; Bisphosphate 3'-nucleotidase 1; BPntase; BPntase 1; epididymis luminal protein 20; HsPIP; Inositol-polyphosphate 1-phosphatase; PAP phosphatase; PAP-inositol 1,4-phosphatase; PAP-inositol-1,4-phosphatase; PIP; RnPIP; scHAL2 analogous 3; testicular tissue protein Li 29
Gene Aliases: BPNT1; BPntase; HEL20; PIP; Sal3
UniProt ID: (Human) O95861, (Mouse) Q9Z0S1, (Rat) Q9Z1N4
Entrez Gene ID: (Human) 10380, (Mouse) 23827, (Rat) 64473
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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