Active Motif

BRD3 Polyclonal Antibody

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BRD3 Antibody (61489) in WB

BRD3 antibody (pAb) tested by Western blot. Detection of BRD3 by Western blot analysis. Lane 1: Whole cell extract of HeLa cells (20 µg). Lane 2: Whole cell extract of NIH-3T3 cells. Both probed with BRD3 antibody (pAb) at a 1:500 dilution.

BRD3 Antibody in ChIP-Sequencing (ChIP-Seq)

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Product Details

61489

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

ChIP assay (ChIP)

10 µL

ChIP-sequencing (ChIP-Seq)

10 µL

View 1 publication 1 publication

Miscellaneous PubMed (Misc)

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

This antibody was raised against a peptide within the C-terminal region of mouse BRD3.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.5, with 30% glycerol

Contains

0.035% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2737028

Target Information

This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Effects of epigenetic pathway inhibitors on corticotroph tumour AtT20 cells.

Endocrine-related cancer

Lines KE,Filippakopoulos P,Stevenson M,Müller S,Lockstone HE,Wright B,Knapp S,Buck D,Bountra C,Thakker RV

Research topic: Pituitary carcinoma

Sun Mar 01 00:00:00 EST 2020

Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.

The Journal of biological chemistry

Werner MT,Wang H,Hamagami N,Hsu SC,Yano JA,Stonestrom AJ,Behera V,Zong Y,Mackay JP,Blobel GA

Research topic: Protein turnover

Fri Feb 14 00:00:00 EST 2020

Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Sartor GC,Malvezzi AM,Kumar A,Andrade NS,Wiedner HJ,Vilca SJ,Janczura KJ,Bagheri A,Al-Ali H,Powell SK,Brown PT,Volmar CH,Foster TC,Zeier Z,Wahlestedt C

Research topic: Neurobiology

Wed Jan 23 00:00:00 EST 2019

Inhibition of the BET family reduces its new target gene IDO1 expression and the production of L-kynurenine.

Cell death & disease

Tian CQ,Chen L,Chen HD,Huan XJ,Hu JP,Shen JK,Xiong B,Wang YQ,Miao ZH

Research topic: Cancer, Gene Expression

Fri Jul 19 00:00:00 EDT 2019

Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Sartor GC,Powell SK,Brothers SP,Wahlestedt C

Research topic: Neurobiology, Drug Addiction

Wed Nov 11 00:00:00 EST 2015

Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity.

The Journal of neuroscience : the official journal of the Society for Neuroscience

Sartor GC,Powell SK,Brothers SP,Wahlestedt C

Research topic: Neurobiology, Drug Addiction

Wed Nov 11 00:00:00 EST 2015

Bioinformatics

Protein Aliases: bromodomain-containing 3; Bromodomain-containing FSH-like protein FSRG2; Bromodomain-containing protein 3; bromodomain-containing protein 3 short isoform; RING3-like protein

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Gene Aliases: 2410084F24Rik; AW060456; BRD3; Fsrg2; KIAA0043; ORFX; RING3L; RINGL3

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UniProt ID: (Human) Q15059, (Mouse) Q8K2F0

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Entrez Gene ID: (Human) 8019, (Mouse) 67382

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Function(s)

chromatin binding protein binding lysine-acetylated histone binding

Process(es)

transcription, DNA-templated regulation of transcription from RNA polymerase II promoter covalent chromatin modification regulation of transcription, DNA-templated chromatin modification

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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BRD3 Polyclonal Antibody

BRD3 Antibody (61489) in WB

Product Details

61489

Western Blot (WB)

ChIP assay (ChIP)

ChIP-sequencing (ChIP-Seq)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

Bioinformatics

Performance Guarantee

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