Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: SLAGDEATHH TEDAAEEERL VLLENQKHLP VEEQLKLLLE RLDEVNASKQ SVGRSRRAKM IKKEMTALRR KLAHQRETGR DGPERHGPSS RGSLTPHPAA CDKDGQTD
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; Peregrin; Protein Br140
Gene Aliases: BR140; BRPF1
UniProt ID: (Human) P55201
Entrez Gene ID: (Human) 7862
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