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Product Details
14879-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BTG1 Fusion Protein Ag6651 (1-171 aa encoded by BC064953)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MHPFYTRAA TMIGEIAAAV SFISKFLRTK GLTSERQLQT FSQSLQELLA EHYKHHWFPE KPCKGSGYRC IRINHKMDPL IGQAAQRIGL SSQELFRLLP SELTLWVDPY EVSYRIGEDG SICVLYEASP AGGSTQNSTN VQMVDSRISC KEELLLGRTS PSKNYNMMTV SG (1-171 aa encoded by BC064953)
Target Information
BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8; 12)(q24; q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Anti-proliferative factor; B-cell translocation gene 1 protein; B-cell translocation gene 1, anti-proliferative; Protein BTG1
Gene Aliases: AI426953; APRO2; AW546738; BTG1
UniProt ID: (Human) P62324, (Rat) Q63073, (Mouse) P62325
Entrez Gene ID: (Human) 694, (Rat) 29618, (Mouse) 12226
regulation of transcription, DNA-templated
negative regulation of cell proliferation
cell migration
negative regulation of cell growth
positive regulation of endothelial cell differentiation
positive regulation of myoblast differentiation
positive regulation of angiogenesis
positive regulation of fibroblast apoptotic process
protein methylation
response to oxidative stress
spermatogenesis
spermatid development
response to peptide hormone
positive regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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