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Product Details
27073-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BUB3 Fusion Protein Ag25608 (205-328 aa encoded by BC005138)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VEYLDPSPE VQKKKYAFKC HRLKENNIEQ IYPVNAISFH NIHNTFATGG SDGFVNIWDP FNKKRLCQFH RYPTSIASLA FSNDGTTLAI ASSYMYEMDD TEHPEDGIFI RQVTDAETKP KSPCT (205-328 aa encoded by BC005138)
Target Information
This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BUB3 budding uninhibited by benzimidazoles 3 homolog; BUB3 mitotic checkpoint protein; budding uninhibited by benomyl; budding uninhibited by benzimidazoles 3 homolog; mitotic checkpoint component; Mitotic checkpoint protein BUB3; OTTHUMP00000020682; testicular tissue protein Li 27
Gene Aliases: Aa2-050; BUB3; BUB3L; hBUB3
UniProt ID: (Human) O43684
Entrez Gene ID: (Human) 9184, (Rat) 361662
mitotic sister chromatid segregation
sister chromatid cohesion
mitotic spindle assembly checkpoint
attachment of spindle microtubules to kinetochore
anaphase-promoting complex-dependent catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
cell division
meiotic cell cycle
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
spindle assembly checkpoint
chromosome segregation
regulation of chromosome segregation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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