Product References
Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer's Disease.
International journal of molecular sciences
Tun X,Wang EJ,Gao Z,Lundberg K,Xu R,Hu D
Thu Mar 16 00:00:00 EDT 2023
Gene Editing Corrects In Vitro a G > A GLB1 Transition from a GM1 Gangliosidosis Patient.
The CRISPR journal
Leclerc D,Goujon L,Jaillard S,Nouyou B,Cluzeau L,Damaj L,Dubourg C,Etcheverry A,Levade T,Froissart R,Dréano S,Guillory X,Eriksson LA,Launay E,Mouriaux F,Belaud-Rotureau MA,Odent S,Gilot D
Wed Feb 01 00:00:00 EST 2023
The Expression of αvβ3 and Osteopontin in Osteoarthritic Knee Cartilage and Their Correlations With Disease Severity and Chondrocyte Senescence.
Applied immunohistochemistry & molecular morphology : AIMM
Cheng C,Tian J,Gao SG,Zhou ZH,Yang RQ,Xiao K,Guo W,Liu L,Yang H,Zhang FJ
Sun Jan 01 00:00:00 EST 2023
The Expression of αvβ3 and Osteopontin in Osteoarthritic Knee Cartilage and Their Correlations With Disease Severity and Chondrocyte Senescence.
Applied immunohistochemistry & molecular morphology : AIMM
Cheng C,Tian J,Gao SG,Zhou ZH,Yang RQ,Xiao K,Guo W,Liu L,Yang H,Zhang FJ
Sun Jan 01 00:00:00 EST 2023
p16INK4a Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Oxidative medicine and cellular longevity
Liang Y,Gu T,Peng S,Lin Y,Liu J,Wang X,Huang X,Zhang X,Zhu J,Zhao L,Fan C,Wang G,Gu X,Lin J
Tue Dec 06 00:00:00 EST 2022
p16INK4a Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Oxidative medicine and cellular longevity
Liang Y,Gu T,Peng S,Lin Y,Liu J,Wang X,Huang X,Zhang X,Zhu J,Zhao L,Fan C,Wang G,Gu X,Lin J
Tue Dec 06 00:00:00 EST 2022
Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death.
Molecules (Basel, Switzerland)
Zhang W,Yang X,Liu J,Pan Y,Zhang M,Chen L
Mon Sep 12 00:00:00 EDT 2022
The fiber diameter traits of Tibetan cashmere goats are governed by the inherent differences in stress, hypoxic, and metabolic adaptations: an integrative study of proteome and transcriptome.
BMC genomics
Zhao B,Wu C,Sammad A,Ma Z,Suo L,Wu Y,Fu X
Mon Mar 07 00:00:00 EST 2022
Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.
Nature communications
Boland S,Swarup S,Ambaw YA,Malia PC,Richards RC,Fischer AW,Singh S,Aggarwal G,Spina S,Nana AL,Grinberg LT,Seeley WW,Surma MA,Klose C,Paulo JA,Nguyen AD,Harper JW,Walther TC,Farese RV
Fri Oct 07 00:00:00 EDT 2022
Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.
Cell death & disease
Zois CE,Hendriks AM,Haider S,Pires E,Bridges E,Kalamida D,Voukantsis D,Lagerholm BC,Fehrmann RSN,den Dunnen WFA,Tarasov AI,Baba O,Morris J,Buffa FM,McCullagh JSO,Jalving M,Harris AL
Tue Jun 28 00:00:00 EDT 2022
TMT-based quantitative N-glycoproteomic analysis reveals glycoprotein protection can improve the quality of frozen bovine sperm.
International journal of biological macromolecules
Wang N,Yang M,He D,Li X,Zhang X,Han B,Liu C,Hai C,Li G,Zhao Y
Sat Oct 01 00:00:00 EDT 2022
Schwann Cells Accelerate Osteogenesis via the Mif/CD74/FOXO1 Signaling Pathway In Vitro.
Stem cells international
Li JQ,Jiang HJ,Su XY,Feng L,Zhan NZ,Li SS,Chen ZJ,Chang BH,Cheng PZ,Yang L,Pei GX
Tue Jan 25 00:00:00 EST 2022
Heat shock protein A12B gene therapy improves perfusion, promotes neovascularization, and decreases fibrosis in a murine model of hind limb ischemia.
Surgery
Thirunavukkarasu M,Tipu Rishi M,Pradeep SR,Swaminathan S,Accorsi D,Palesty JA,Maulik N
Wed Sep 01 00:00:00 EDT 2021
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention.
Communications biology
Vignoli B,Sansevero G,Sasi M,Rimondini R,Blum R,Bonaldo V,Biasini E,Santi S,Berardi N,Lu B,Canossa M
Tue Oct 05 00:00:00 EDT 2021
Galactose-modified duocarmycin prodrugs as senolytics.
Aging cell
Guerrero A,Guiho R,Herranz N,Uren A,Withers DJ,Martínez-Barbera JP,Tietze LF,Gil J
Wed Apr 01 00:00:00 EDT 2020
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation.
Cancer letters
Shen L,Kang L,Wang D,Xun J,Chen C,Du L,Zhang M,Gong J,Mi X,Yue S,Zhang Y,Song X,Xiang R,Zhang Z,Tan X
Sun Mar 01 00:00:00 EST 2020
Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation.
Cancer letters
Shen L,Kang L,Wang D,Xun J,Chen C,Du L,Zhang M,Gong J,Mi X,Yue S,Zhang Y,Song X,Xiang R,Zhang Z,Tan X
Sun Mar 01 00:00:00 EST 2020
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Pain research & management
Tian J,Cheng C,Kuang SD,Su C,Zhao X,Xiong YL,Li YS,Gao SG
Wed Mar 10 00:00:00 EST 2021
Sarcopenia is attenuated by TRB3 knockout in aging mice via the alleviation of atrophy and fibrosis of skeletal muscles.
Journal of cachexia, sarcopenia and muscle
Shang GK,Han L,Wang ZH,Liu YP,Yan SB,Sai WW,Wang D,Li YH,Zhang W,Zhong M
Sat Aug 01 00:00:00 EDT 2020
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Cell reports
Balakrishnan I,Danis E,Pierce A,Madhavan K,Wang D,Dahl N,Sanford B,Birks DK,Davidson N,Metselaar DS,Meel MH,Lemma R,Donson A,Vijmasi T,Katagi H,Sola I,Fosmire S,Alimova I,Steiner J,Gilani A,Hulleman E,Serkova NJ,Hashizume R,Hawkins C,Carcaboso AM,Gupta N,Monje M,Jabado N,Jones K,Foreman N,Green A,Vibhakar R,Venkataraman S
Tue Oct 20 00:00:00 EDT 2020
Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function.
Aging
Wang J,Li S,Wang J,Wu F,Chen Y,Zhang H,Guo Y,Lin Y,Li L,Yu X,Liu T,Zhao Y
Mon Jan 06 00:00:00 EST 2020
Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription.
Theranostics
Zou G,Zhang X,Wang L,Li X,Xie T,Zhao J,Yan J,Wang L,Ye H,Jiao S,Xiang R,Shi Y
Tue May 18 00:00:00 EDT 2021
Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
Stem cell research & therapy
Xu P,Xin Y,Zhang Z,Zou X,Xue K,Zhang H,Zhang W,Liu K
Wed Jul 01 00:00:00 EDT 2020
Cardiac glycosides are broad-spectrum senolytics.
Nature metabolism
Guerrero A,Herranz N,Sun B,Wagner V,Gallage S,Guiho R,Wolter K,Pombo J,Irvine EE,Innes AJ,Birch J,Glegola J,Manshaei S,Heide D,Dharmalingam G,Harbig J,Olona A,Behmoaras J,Dauch D,Uren AG,Zender L,Vernia S,Martínez-Barbera JP,Heikenwalder M,Withers DJ,Gil J
Fri Nov 01 00:00:00 EDT 2019
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Signal transduction and targeted therapy
Li Y,Li X,Cao M,Jiang Y,Yan J,Liu Z,Yang R,Chen X,Sun P,Xiang R,Wang L,Shi Y
Fri Jan 29 00:00:00 EST 2021
Seryl tRNA synthetase cooperates with POT1 to regulate telomere length and cellular senescence.
Signal transduction and targeted therapy
Li Y,Li X,Cao M,Jiang Y,Yan J,Liu Z,Yang R,Chen X,Sun P,Xiang R,Wang L,Shi Y
Fri Jan 29 00:00:00 EST 2021
Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways.
Bioscience reports
Wu Y,Cai Q,Li W,Cai Z,Liu Y,Li H,Pang J,Chen Y
Fri Aug 30 00:00:00 EDT 2019
β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.
Arteriosclerosis, thrombosis, and vascular biology
Turlo KA,Scapa J,Bagher P,Jones AW,Feil R,Korthuis RJ,Segal SS,Iruela-Arispe ML
Tue Oct 01 00:00:00 EDT 2013
β1-integrin is essential for vasoregulation and smooth muscle survival in vivo.
Arteriosclerosis, thrombosis, and vascular biology
Turlo KA,Scapa J,Bagher P,Jones AW,Feil R,Korthuis RJ,Segal SS,Iruela-Arispe ML
Tue Oct 01 00:00:00 EDT 2013
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Experimental gerontology
Büchner N,Ale-Agha N,Jakob S,Sydlik U,Kunze K,Unfried K,Altschmied J,Haendeler J
Tue Jan 01 00:00:00 EST 2013
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Experimental gerontology
Büchner N,Ale-Agha N,Jakob S,Sydlik U,Kunze K,Unfried K,Altschmied J,Haendeler J
Tue Jan 01 00:00:00 EST 2013
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
Atherosclerosis
Werner C,Gensch C,Pöss J,Haendeler J,Böhm M,Laufs U
Sun May 01 00:00:00 EDT 2011
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
Atherosclerosis
Werner C,Gensch C,Pöss J,Haendeler J,Böhm M,Laufs U
Sun May 01 00:00:00 EDT 2011
