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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BRCA2-interacting transcriptional repressor EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; protein EMSY; similar to EMSY protein
Gene Aliases: 2310016L09Rik; AU019521; AU019557; C11orf30; EMSY; GL002
UniProt ID: (Mouse) Q8BMB0, (Human) Q4G109
Entrez Gene ID: (Mouse) 233545, (Human) 56946, (Rat) 361607
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