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Product Details
PA5-96516
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_0645782)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808318
Product Specific Information
Immunogen sequence: SLMEAQIDTN VEHMIVDPPK KALATSMLTG EAGSLPSTHM VVAGMANSTP QQQKCRESCS SPSTVGSSLT TRKIDPPAVP ATGQFMRIQN VGQKKAEESP AEIIIQAIPQ YAIPCHSSSN VVVEPSGLLE LNNFTSQQLD DEETAMEQDI DSSTEDGTEP SPSQSSAERS; Positive Samples: Mouse lung, Mouse brain, Mouse spleen, Mouse ovary, Mouse kidney; Cellular Location: Nucleus
Target Information
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BRCA2-interacting transcriptional repressor EMSY; EMSY BRCA2-interacting transcriptional repressor; EMSY protein; EMSY, BRCA2-interacting transcriptional repressor; FLJ90741; protein EMSY
Gene Aliases: 2310016L09Rik; AU019521; AU019557; C11orf30; EMSY; GL002
UniProt ID: (Mouse) Q8BMB0, (Human) Q4G109
Entrez Gene ID: (Mouse) 233545, (Human) 56946
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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