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Product Details
H00080183-D01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
C13orf18 (AAH43488.1, 1 a.a. approximately 595 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MVSNHYFLLC VNLPLREIHT PGPSPSCLGD SLAETTLSED TTDSVGSASP HGSSEKSSSF SLSSTEVHMV RPGYSHRVSL PTSPRILATS PYPETDSAFF EPSHLTSAAD EGAVQVSRRT ISSNSFSPEV FVLPVDVEKE NAHFYVADMI ISAMEKMKCN ILSQQQTESW SKEVSGLLGS DQPDSEMTFD TNIKQESGSS TSSYSGYEGC AVLQVSPVTE TRTYHDVKEI CKCDVDEFVI LELGDFNDIT ETCSCSCSSS KSVTYEPDFN SAELLAKELY RVFQKCWILS VVNSQLAGSL SAAGSIVVNE ECVRKDFESS MNVVQEIKFK SRIRGTEDWA PPRFQIIFNI HPPLKRDLVV AAQNFFCAGC GTPVEPKFVK RLRYCEYLGK YFCDCCHSYA ESCIPARILM MWDFKKYYVS NFSKQLLDSI WHQPIFNLLS IGQSLYAKAK ELDRVKEIQE QLFHIKKLLK TCRFANSALK EFEQVPGHLT DELHLFSLED LVRIKKGLLA PLLKDILKAS LAHVAGCELC QGKGFICEFC QNTTVIFPFQ TATCRRCSAC RACFHKQCFQ SSECPRCARI TARRKLLESV ASAAT
Target Information
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA0226-like; Pacer; Protein associated with UVRAG as autophagy enhancer; Protein Rubicon-like; uncharacterized protein KIAA0226-like
Gene Aliases: C13orf18; Gm744; Gm911; KIAA0226L; RUBCNL
UniProt ID: (Human) Q9H714
Entrez Gene ID: (Mouse) 271221, (Human) 80183
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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