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Product Details
BS-15079R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human C1orf86, amino acids 101-180.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FANCA-associated protein of 20 kDa; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa; likely orthologue of H. sapiens chromosome 1 open reading frame 86 (C1orf86)
Gene Aliases: C1orf86; FAAP20; FP7162
UniProt ID: (Mouse) Q3UN58, (Human) Q6NZ36, (Rat) D4AAA5
Entrez Gene ID: (Mouse) 67513, (Human) 199990, (Rat) 362678
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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