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Invitrogen
C2orf33 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
C2orf33 Antibody (PA5-67357) in ICC/IF
Immunofluorescence analysis of C2orf33 was performed using HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with C2orf33 Rabbit Polyclonal Antibody (Product # PA5-67357) at 4µg/mL dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution ... View More
Product Details
PA5-67357
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human C2orf33. Recombinant protein control fragment (Product #RP-108010).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2664710
Product Specific Information
Immunogen sequence: DLIQSTPFKPL ALKTPPRVLT LSERPLDFLD LERPPTTPQN EEIRAVGRLK RERSMSENAV RQNGQLVRND SLWH
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 96%.
Target Information
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mitochondrial fission factor
Gene Aliases: AD030; AD033; C2orf33; GL004; MFF
UniProt ID: (Human) Q9BVZ1
Entrez Gene ID: (Human) 56947
mitochondrial fission
release of cytochrome c from mitochondria
protein targeting to mitochondrion
mitochondrial fusion
regulation of mitochondrion organization
peroxisome fission
mitochondrial fragmentation involved in apoptotic process
protein homooligomerization
mitochondrion morphogenesis
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
positive regulation of protein targeting to membrane
regulation of peroxisome organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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