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C6 Antibody (PA5-117356) in WB
Western blot analysis of C6 in Rat plasma (50 µg). Samples were separated with 7.5% SDS-PAGE and incubated in C6 polyclonal antibody (Product # PA5-117356) using a dilution of 1:1,000, followed by HRP-conjugated anti-rabbit IgG. Detection was performed with Trident ECL plus-Enhanced.
Product Details
PA5-117356
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human C6. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol, 1% BSA
Contains
0.025% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901986
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
C6 is a component of complement cascade. It is part of the membrane attack complex which can insert into the cell membrane and cause cell to lyse. People with C6 deficiency are prone to bacterial infection. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Complement component C6
Gene Aliases: C6
UniProt ID: (Human) P13671, (Rat) Q811M5
Entrez Gene ID: (Human) 729, (Rat) 24237
in utero embryonic development
positive regulation of activation of membrane attack complex
complement activation
complement activation, classical pathway
cytolysis
regulation of complement activation
innate immune response
positive regulation of angiogenesis
immune response
positive regulation of apoptotic process
positive regulation of complement activation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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