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Product Details
MA5-42846
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7J2L5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 83-182 of human CD3G (P09693).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911987
Product Specific Information
Positive test controls include: Rat lung, Rat spleen.
Immunogen sequence: GMYQCKGSQN KSKPLQVYYR MCQNCIELNA ATISGFLFAE IVSIFVLAVG VYFIAGQDGV RQSRASDKQT LLPNDQLYQP LKDREDDQYS HLQGNQLRRN
Target Information
CD3G is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in the CD3G gene are associated with T cell immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD3 antigen, gamma polypeptide; CD3 gamma-chain; CD3 molecule, gamma polypeptide; CD3g; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain
Gene Aliases: CD3-GAMMA; CD3G; IMD17; T3G
UniProt ID: (Human) P09693, (Rat) Q64159
Entrez Gene ID: (Human) 917, (Rat) 300678
establishment or maintenance of cell polarity
cell surface receptor signaling pathway
biological_process
protein transport
regulation of lymphocyte apoptotic process
protein complex assembly
T cell costimulation
Fc-gamma receptor signaling pathway involved in phagocytosis
T cell activation
regulation of immune response
T cell receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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