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The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: caudal type homeo box 2; caudal type homeo box transcription factor 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX-3; HGNC:1806; Homeobox protein CDX-2; homeobox protein miniCDX2; homeobox transcription factor
Gene Aliases: CDX-2; CDX-3; CDX2; CDX2/AS; CDX3
UniProt ID: (Human) Q99626, (Mouse) P43241
Entrez Gene ID: (Pig) 100127132, (Bovine) 618679, (Chicken) 374205, (Human) 1045, (Mouse) 12591, (Rat) 66019
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