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Invitrogen
CK2 alpha-1 Recombinant Rabbit Monoclonal Antibody (2B6)
FIGURE: 1 / 1
CK2 alpha-1 Antibody (MA5-49942) in WB
Western blot analysis of CK2 alpha-1 in NIH/3T3 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HeLa whole cell lysate, A549 whole cell lysate, U-87 whole cell lysate using a dilution of 1:1,000. Samples were incubated with CK2 alpha-1 monoclonal antibody (Product # MA5-49942). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 46, 30 kDa. Observed band size: 45 kDa.
Product Details
MA5-49942
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
2B6
Immunogen
A synthesized peptide derived from human CKII alpha
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3093715
Target Information
CSNK2A1 is a serine/threonine protein kinase that phosphorylates acidic proteins. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by CK2 alpha-1 represents the alpha subunit. While CK2 alpha-1 is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for CK2 alpha-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 2 alpha; casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; Casein kinase II subunit alpha; casein kinase II, alpha 1 polypeptide; casein kinase II, alpha 1 related sequence 4; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; protein kinase CK2
Gene Aliases: CK2A1; CKII; Ckiia; CSNK2A1; Csnk2a1-rs4; CSNK2A3
UniProt ID: (Human) P68400, (Mouse) Q60737
Entrez Gene ID: (Human) 1457, (Mouse) 12995
protein phosphorylation
positive regulation of cell proliferation
positive regulation of Wnt signaling pathway
positive regulation of cell growth
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of protein catabolic process
protein autophosphorylation
regulation of catalytic activity
mitotic spindle checkpoint
transcription, DNA-templated
regulation of transcription, DNA-templated
protein folding
apoptotic process
signal transduction
Wnt signaling pathway
rhythmic process
chaperone-mediated protein folding
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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