Invitrogen

CREBRF Polyclonal Antibody

2 Published Figures

3 References

View all (2) CREBRF antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)
Published Figures (2)

FIGURE: 1 / 3

CREBRF Antibody (PA5-68552) in WB

Western blot analysis of CREBRF on human lung cells. The sample was probed with a CREBRF polyclonal antibody (Product # PA5-68552) using a primary antibody dilution of 0.2-1.0 µg/mL.

CREBRF Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

PA5-68552

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Pig

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the middle region of human CREBRF

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2689327

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Target Information

Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR). Represses the transcriptional activity of CREB3 during the UPR. Recruits CREB3 into nuclear foci.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC.

Cancers

Shibata T,Cao DY,Dar TB,Ahmed F,Bhat SA,Veiras LC,Bernstein EA,Khan AA,Chaum M,Shiao SL,Tourtellotte WG,Giani JF,Bernstein KE,Cui X,Vail E,Khan Z

PA5-68552 was used in Western Blotting to demonstrate a novel miR124-3p- and miR766-3p-based biological mechanism governing treatment-resistant HNSCC, which can be targeted to improve clinical outcomes in HNSCC.

Thu Oct 27 00:00:00 EDT 2022

miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC.

Cancers

Shibata T,Cao DY,Dar TB,Ahmed F,Bhat SA,Veiras LC,Bernstein EA,Khan AA,Chaum M,Shiao SL,Tourtellotte WG,Giani JF,Bernstein KE,Cui X,Vail E,Khan Z

Thu Oct 27 00:00:00 EDT 2022

miR766-3p and miR124-3p Dictate Drug Resistance and Clinical Outcome in HNSCC.

Cancers

Shibata T,Cao DY,Dar TB,Ahmed F,Bhat SA,Veiras LC,Bernstein EA,Khan AA,Chaum M,Shiao SL,Tourtellotte WG,Giani JF,Bernstein KE,Cui X,Vail E,Khan Z

Thu Oct 27 00:00:00 EDT 2022

Generation of a genetically modified pig model with CREBRF^R457Q variant.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Li Y,Wang H,Chen H,Liao Y,Gou S,Yan Q,Zhuang Z,Li H,Wang J,Suo Y,Lan T,Liu Y,Zhao Y,Zou Q,Nie T,Hui X,Lai L,Wu D,Fan N

PA5-68552 was used in Western Blotting to investigate the functional consequences of the CREBRF variant by introducing the corresponding human mutation R457Q into the porcine genome.

Tue Nov 01 00:00:00 EDT 2022

Bioinformatics

Protein Aliases: adult retina protein; CREB3 regulatory factor; LRF; Luman recruitment factor; luman-recruiting factor; luman/CREB3 recruitment factor; UPF0474 protein C5orf41

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Gene Aliases: C5orf41; CREBRF; LRF

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UniProt ID: (Human) B3KW49

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Entrez Gene ID: (Human) 153222

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Function(s)

transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding

Process(es)

transcription, DNA-templated regulation of transcription, DNA-templated transport response to unfolded protein maternal behavior negative regulation of glucocorticoid mediated signaling pathway positive regulation of prolactin signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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CREBRF Polyclonal Antibody

CREBRF Antibody (PA5-68552) in WB

Product Details

PA5-68552

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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