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Product Details
14686-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CRMP2 Fusion Protein Ag5985 (223-572 aa encoded by BC056408)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: HVLSRPEEV EAEAVNRAIT IANQTNCPLY ITKVMSKSSA EVIAQARKKG TVVYGEPITA SLGTDGSHYW SKNWAKAAAF VTSPPLSPDP TTPDFLNSLL SCGDLQVTGS AHCTFNTAQK AVGKDNFTLI PEGTNGTEER MSVIWDKAVV TGKMDENQFV AVTSTNAAKV FNLYPRKGRI AVGSDADLVI WDPDSVKTIS AKTHNSSLEY NIFEGMECRG SPLVVISQGK IVLEDGTLHV TEGSGRYIPR KPFPDFVYKR IKARSRLAEL RGVPRGLYDG PVCEVSVTPK TVTPASSAKT SPAKQQAPPV RNLHQSGFSL SGAQIDDNIP RRTTQRIVAP PGGRANITSL G (223-572 aa encoded by BC056408)
Target Information
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; dihydropyrimidinase-like 2; Dihydropyrimidinase-related protein 2; DPYL2; DRP-2; N2A3; TOAD-64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP-2; Unc-33-like phosphoprotein 2
Gene Aliases: AI851130; CRMP-2; CRMP2; DHPRP2; DPYSL2; DRP-2; DRP2; Musunc33; N2A3; TOAD-64; ULIP-2; ULIP2
UniProt ID: (Human) Q16555, (Rat) P47942, (Mouse) O08553
Entrez Gene ID: (Human) 1808, (Rat) 25416, (Mouse) 12934
response to amphetamine
nucleobase-containing compound metabolic process
endocytosis
cytoskeleton organization
signal transduction
nervous system development
axon guidance
positive regulation of glutamate secretion
spinal cord development
olfactory bulb development
regulation of axon extension
response to cocaine
response to drug
synaptic vesicle transport
pyrimidine nucleobase catabolic process
brain development
regulation of neuron projection development
regulation of neuron differentiation
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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