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Invitrogen
CRMP2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
CRMP2 Antibody (PA5-29728) in ICC/IF
Immunofluorescence analysis of CRMP2 was performed using 70% confluent log phase Neuro-2a cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with CRMP2 Rabbit Polyclonal Antibody (Product # PA5-29728) at 5 µg/mL in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain), Superclonal™ Recombinant Secondary Antibody, Alexa Fluor 488 (Product #... View More
Product Details
PA5-29728
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 219 of Human CRMP2
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2547202
Product Specific Information
Recommended positive controls: U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, rat brain.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (87%), Chicken (95%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; dihydropyrimidinase-like 2; Dihydropyrimidinase-related protein 2; DPYL2; DRP-2; N2A3; TOAD-64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP-2; Unc-33-like phosphoprotein 2
Gene Aliases: AI851130; CRMP-2; CRMP2; DHPRP2; DPYSL2; DRP-2; DRP2; Musunc33; N2A3; TOAD-64; ULIP-2; ULIP2
UniProt ID: (Human) Q16555, (Rat) P47942, (Mouse) O08553
Entrez Gene ID: (Human) 1808, (Rat) 25416, (Mouse) 12934
response to amphetamine
nucleobase-containing compound metabolic process
endocytosis
cytoskeleton organization
signal transduction
nervous system development
axon guidance
positive regulation of glutamate secretion
spinal cord development
olfactory bulb development
regulation of axon extension
response to cocaine
response to drug
synaptic vesicle transport
pyrimidine nucleobase catabolic process
brain development
regulation of neuron projection development
regulation of neuron differentiation
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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