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Invitrogen
CRMP2 Monoclonal Antibody (OTI5D7)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 5
CRMP2 Antibody (MA5-27498) in WB
Western blot was performed using Anti-CRMP2 Monoclonal Antibody (OTI5D7), eBioscience™ (Product # MA5-27498) and a 60 kDa band corresponding to CRMP2 was observed across cell lines and tissues tested except MCF-7 and SK-BR-3 which are reported to be low protein expressing cell lines. Membrane enriched extracts (30 µg lysate) of PC-12 (Lane 1), Neuro-2a (Lane 2) and SH-SY5Y (Lane 3), U-87 MG (Lane 4), MCF-7 (Lane 5), MCF 10A (Lane 6), SK-BR-3 (Lane 7), tissue extracts of Mouse Brain (Lane 8) and Rat Brain (Lane 9) were electrophoresed using... View More
Product Details
MA5-27498
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI5D7
Immunogen
Human recombinant protein fragment corresponding to amino acids 13-490 of DPYSL2 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723014
Target Information
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; dihydropyrimidinase-like 2; Dihydropyrimidinase-related protein 2; DPYL2; DRP-2; N2A3; TOAD-64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP-2; Unc-33-like phosphoprotein 2
Gene Aliases: AI851130; CRMP-2; CRMP2; DHPRP2; DPYSL2; DRP-2; DRP2; Musunc33; N2A3; TOAD-64; ULIP-2; ULIP2
UniProt ID: (Human) Q16555, (Rat) P47942, (Mouse) O08553
Entrez Gene ID: (Human) 1808, (Rat) 25416, (Mouse) 12934
response to amphetamine
nucleobase-containing compound metabolic process
endocytosis
cytoskeleton organization
signal transduction
nervous system development
axon guidance
positive regulation of glutamate secretion
spinal cord development
olfactory bulb development
regulation of axon extension
response to cocaine
response to drug
synaptic vesicle transport
pyrimidine nucleobase catabolic process
brain development
regulation of neuron projection development
regulation of neuron differentiation
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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