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Product Details
BS-6365R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human CROT/COT, amino acids 201-275.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4, 8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COT; peroxisomal carnitine acyltransferase; Peroxisomal carnitine O-octanoyltransferase
Gene Aliases: 1200003H03Rik; COT; CROT
UniProt ID: (Human) Q9UKG9, (Mouse) Q9DC50, (Rat) P11466
Entrez Gene ID: (Human) 54677, (Mouse) 74114, (Rat) 83842
generation of precursor metabolites and energy
fatty acid metabolic process
fatty acid beta-oxidation
carnitine metabolic process
response to organonitrogen compound
fatty acid transport
coenzyme A metabolic process
fatty acid beta-oxidation using acyl-CoA oxidase
response to drug
medium-chain fatty acid metabolic process
lipid metabolic process
transport
medium-chain fatty acid transport
long-chain fatty acid transport
Performance Guarantee
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