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Invitrogen
Connexin 36 Recombinant Rabbit Monoclonal Antibody (12H11L18)
Advanced Verification
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 4
Connexin 36 Antibody (701630) in ICC/IF
Immunofluorescence was performed on fixed and permeabilized SH-SY5Y cells treated with retinoic acid (10 uM/72 hours) for detection of Connexin 36 using Anti-Connexin 36 Recombinant Rabbit Monoclonal Antibody (Product # 701630, 2 µg/mL) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cel... View More
Product Details
701630
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
12H11L18
Immunogen
Peptides corresponding to Human GJD2 (aa 288-304, 304-319)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2576615
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Goat and Rabbit.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Connexin-36 (CX36), is a member of the connexin gene family that is expressed predominantly in mammalian neurons. Connexins associate in groups of 6 and are organized radially around a central pore to form connexons. Each gap junction intercellular channel is formed by the conjunction of 2 connexons. Mutations in connexin-encoding genes can lead to functional and developmental abnormalities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: connexin 36; Connexin-36; Cx36; Gap junction alpha-9 protein; Gap junction delta-2 protein; gap junction membrane channel protein alpha 9; gap junction protein, delta 2, 36kDa; GJA10
Gene Aliases: CX36; GJA9; GJD2
UniProt ID: (Human) Q9UKL4, (Rat) O70610
Entrez Gene ID: (Human) 57369, (Rat) 50564
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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