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DAO Polyclonal Antibody

DAO Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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DAO Antibody (13273-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human colon tissue slide using 13273-1-AP ( DAO Antibody) at dilution of 1:200 (under 40x lens).

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Product Details

13273-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:500

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:400

Immunocytochemistry (ICC/IF)

View 1 publication 1 publication

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

DAO Fusion Protein Ag3973 (24-347 aa encoded by BC029057)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: HSVLQPLDI KVYADRFTPL TTTDVAAGLW QPYLSDPNNP QEADWSQQTF DYLLSHVHSP NAENLGLFLI SGYNLFHEAI PDPSWKDTVL GFRKLTPREL DMFPDYGYGW FHTSLILEGK NYLQWLTERL TERGVKFFQR KVESFEEVAR EGADVIVNCT GVWAGALQRD PLLQPGRGQI MKVDAPWMKH FILTHDPERG IYNSPYIIPG TQTVTLGGIF QLGNWSELNN IQDHNTIWEG CCRLEPTLKN ARIIGERTGF RPVRPQIRLE REQLRTGPSN TEVIHNYGHG GYGLTIHWGC ALEAAKLFGR ILEEKKLSRM PPSHL (24-347 aa encoded by B C029057)

Target Information

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Renal histaminergic system and acute effects of histamine receptor 2 blockade on renal damage in the Dahl salt-sensitive rat.

American journal of physiology. Renal physiology

Spires DR,Schibalski RS,Domondon M,Clarke C,Perez S,Anwar F,Burns E,Saeed MI,Walton SD,Zamaro AS,Amoah T,Arkhipov SN,Christopher CJ,Campagna SR,Mattson DL,Pavlov TS,Ilatovskaya DV

Sat Jul 01 00:00:00 EDT 2023

Renal histaminergic system and acute effects of histamine receptor 2 blockade on renal damage in the Dahl salt-sensitive rat.

American journal of physiology. Renal physiology

Spires DR,Schibalski RS,Domondon M,Clarke C,Perez S,Anwar F,Burns E,Saeed MI,Walton SD,Zamaro AS,Amoah T,Arkhipov SN,Christopher CJ,Campagna SR,Mattson DL,Pavlov TS,Ilatovskaya DV

Sat Jul 01 00:00:00 EDT 2023

Renal histaminergic system and acute effects of histamine receptor 2 blockade on renal damage in the Dahl salt-sensitive rat.

American journal of physiology. Renal physiology

Spires DR,Schibalski RS,Domondon M,Clarke C,Perez S,Anwar F,Burns E,Saeed MI,Walton SD,Zamaro AS,Amoah T,Arkhipov SN,Christopher CJ,Campagna SR,Mattson DL,Pavlov TS,Ilatovskaya DV

Sat Jul 01 00:00:00 EDT 2023

Renal histaminergic system and acute effects of histamine receptor 2 blockade on renal damage in the Dahl salt-sensitive rat.

American journal of physiology. Renal physiology

Spires DR,Schibalski RS,Domondon M,Clarke C,Perez S,Anwar F,Burns E,Saeed MI,Walton SD,Zamaro AS,Amoah T,Arkhipov SN,Christopher CJ,Campagna SR,Mattson DL,Pavlov TS,Ilatovskaya DV

Sat Jul 01 00:00:00 EDT 2023

Functional role of histamine receptors in the renal cortical collecting duct cells.

American journal of physiology. Cell physiology

Sudarikova AV,Fomin MV,Sultanova RF,Zhao Y,Perez S,Domondon M,Shamatova M,Lysikova DV,Spires DR,Ilatovskaya DV

Fri Apr 01 00:00:00 EDT 2022

l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H₂S formation.

Brain, behavior, and immunity

Xin D,Chu X,Bai X,Ma W,Yuan H,Qiu J,Liu C,Li T,Zhou X,Chen W,Liu D,Wang Z

Mon Oct 01 00:00:00 EDT 2018

l-Cysteine suppresses hypoxia-ischemia injury in neonatal mice by reducing glial activation, promoting autophagic flux and mediating synaptic modification via H₂S formation.

Brain, behavior, and immunity

Xin D,Chu X,Bai X,Ma W,Yuan H,Qiu J,Liu C,Li T,Zhou X,Chen W,Liu D,Wang Z

Mon Oct 01 00:00:00 EDT 2018

d-Cysteine promotes dendritic development in primary cultured cerebellar Purkinje cells via hydrogen sulfide production.

Molecular and cellular neurosciences

Seki T,Sato M,Konno A,Hirai H,Kurauchi Y,Hisatsune A,Katsuki H

Sat Dec 01 00:00:00 EST 2018

Bioinformatics

Protein Aliases: AOC1; D-amino acid oxidase 1; D-amino-acid oxidase; DAAO; DAMOX

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Gene Aliases: AI987963; DAAO; DAMOX; DAO; Dao-1; Dao1; OXDA

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UniProt ID: (Human) P14920, (Rat) O35078, (Mouse) P18894

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Entrez Gene ID: (Human) 1610, (Rat) 114027, (Mouse) 13142

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Function(s)

D-amino-acid oxidase activity receptor binding protein binding protein dimerization activity cofactor binding FAD binding oxidoreductase activity oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor oxidase

Process(es)

proline catabolic process D-serine catabolic process dopamine biosynthetic process D-amino acid metabolic process glyoxylate metabolic process oxidation-reduction process D-alanine catabolic process D-serine metabolic process leucine metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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DAO Polyclonal Antibody

DAO Antibody (13273-1-AP) in IHC (P)

Product Details

13273-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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