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DCAF7 Antibody (PA5-77024) in IHC (P)
Immunohistochemistry analysis of DCAF7 in paraffin-embedded human lung cancer. Samples were incubated with DCAF7 polyclonal antibody (Product # PA5-77024) using a dilution of 1:150. Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-77024
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human DCAF7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2720751
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR68 (WD repeat-containing protein 68), also known as DCAF7 (DDB1- and CUL4- associated factor 7), HAN11 or WDR68, is a 342 amino acid protein that belongs to the WD repeat DCAF7 family and contains 4 WD repeats. Localizing to the cytoplasm and nucleus, WDR68 is involved in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B and Dia 1. WDR68 is involved in craniofacial development, and may be involved in skin development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DDB1- and CUL4-associated factor 7; human anthocyanin; seven-WD-repeat protein of the AN11 family-1; WD repeat domain 68; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog; WD-repeat protein
Gene Aliases: 1700012F10Rik; 2610037L01Rik; AN11; C86529; DCAF7; HAN11; RGD1305140; SWAN-1; WDR68
UniProt ID: (Human) P61962, (Mouse) P61963
Entrez Gene ID: (Human) 10238, (Mouse) 71833, (Rat) 303602
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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