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Product Details
26978-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DCDC2 Fusion Protein Ag25577 (351-476 aa encoded by BC050704)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EDGEKANKD AEQKEDFSGM NGDLEEEGGR EATDAPEQVE EILDHSEQQA RPARVNGGTD EENGEELQQV NNELQLVLDK ERKSQGAGSG QDEADVDPQR PPRPEVKITS PEENENNQQN KDYAAVA (351-476 aa encoded by BC050704 )
Target Information
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains. The doublecortin domain has been demonstrated to bind tubulin and enhance microtubule polymerization. Mutations in this gene have been associated with Reading Disability, also referred to as developmental dyslexia. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Doublecortin domain-containing protein 2; HGNC:18141; MGC54817; Protein RU2S
Gene Aliases: AW492955; DCDC2; DCDC2A; DFNB66; KIAA1154; NPHP19; RU2; RU2S
UniProt ID: (Human) Q9UHG0, (Mouse) Q5DU00
Entrez Gene ID: (Human) 51473, (Mouse) 195208
neuron migration
cellular defense response
sensory perception of sound
cell projection organization
regulation of Wnt signaling pathway
intracellular signal transduction
positive regulation of smoothened signaling pathway
regulation of cilium assembly
nervous system development
visual learning
dendrite morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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