Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 4
DLX2 Antibody (PA5-85547) in ICC/IF
DLX2 Polyclonal Antibody detects DLX2 protein by immunofluorescent analysis. Sample: DIV9 rat cortical neuron and Glia cell cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: DLX2 stained by DLX2 Polyclonal Antibody (Product # PA5-85547) diluted at 1:250. Red: Tau, a Axon marker, stained by Tau antibody [GT287] diluted at 1:500. Blue: Fluoroshield with DAPI .
Product Details
PA5-85547
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human DLX2.
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792687
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (93%), Bovine (95%).
Positive Control: human DLX2-transfected 293T.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DII A; distal-less homeo box 2; Homeobox protein DLX-2; Homeobox protein TES-1
Gene Aliases: AW121999; Dlx-2; DLX2; TES-1; TES1
UniProt ID: (Human) Q07687, (Mouse) P40764
Entrez Gene ID: (Human) 1746, (Mouse) 13392
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
single-stranded RNA binding
protein binding
DNA binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
brain development
proximal/distal pattern formation
subpallium development
hippocampus development
olfactory bulb development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron fate commitment
odontogenesis of dentin-containing tooth
negative regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
embryonic cranial skeleton morphogenesis
negative regulation of oligodendrocyte differentiation
branching morphogenesis of a nerve
cartilage development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
multicellular organism development
forebrain neuron differentiation
cerebral cortex GABAergic interneuron differentiation
cell differentiation
embryonic skeletal system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support