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Product Details
11144-MSM1-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2H12/4
Immunogen
Recombinant full-length human DMC1 protein.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4° C, do not freeze
Shipping conditions
Wet ice
Target Information
DMC1 is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this protein is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: disrupted meiotic cDNA 1 homolog; disrupted meiotic cDNA1, yeast, homolog of; DMC 1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1 homologue; HsLim15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473; RP1-199H16.4
Gene Aliases: DCM1; dJ199H16.1; DMC1; DMC1H; LIM15; Mei11; sgdp
UniProt ID: (Human) Q14565, (Mouse) Q61880
Entrez Gene ID: (Human) 11144, (Bovine) 618398, (Mouse) 13404, (Rat) 362960
DNA recombinase assembly
ovarian follicle development
oocyte maturation
mitotic recombination
meiotic nuclear division
synapsis
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
female gamete generation
response to ionizing radiation
strand invasion
chromosome organization involved in meiotic cell cycle
DNA metabolic process
DNA repair
cell cycle
gamete generation
meiotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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